Laboratories investigating dental and bone diseases or orthopedic implant devices have used fluorochrome labels to quantify bone growth for over 40 years. Bone fixation with 10% neutral buffered formalin has been used by many of these laboratories. Routine practice has been to fix the bone samples ...
For PET imaging, this is a problem, because it will increase the nonspecific signal derived from radioactivity in blood. When engineered into bispecific formats, i.e. with the addition of an antibody fragment that binds to TfR, the long half-life of IgG antibodies is reduced, although it ...
Availability of a simple 1-step labeling process would lead to benefits in logistics and clinical use of the tracer. A method of using a ready-to-use vial is a new trend emerging in the last years. It may enable a very easy, short and efficient radiolabeling process. Several cold kits f...
Stimulation is indirect since osteoclasts do not have a receptor for PTH; rather, PTH binds to osteoblasts, the cells responsible for creating bone. Binding stimulates osteoblasts to increase their expression of RANKL, which can bind to osteoclast precursors containing RANK, a receptor for RANKL. ...
CXCR3 is a chemokine receptor and is expressed in innate and adaptive immune cells. It promotes the recruitment of T-lymphocytes and other immune cells to the inflammatory site in response to the binding of cognate chemokines. Upregulation of CXCR3 and i
24 Abstracts of 37th Annual Meeting A1 A SCREENING METHOD FOR FRAGILE X MUTATION: DETECTION OF THE CGG REPEAT IN FMR-1 GENE BY PCR WITH BIOTIN-LABELED PRIMER. 9 ..Eiji NANBA, K o u s a k u OHNO a n d K e n z o TAKESHITA Division of Child Neurology, Institute of Neurological ...
LONG, SCOTT Attorney, Agent or Firm: LOGINOV & ASSOCIATES, PLLC (SHERIDAN, WYOMING, US) Claims: What is claimed is: 1.A medical treatment method for a tumor in a human body comprising the steps of:determining a condition of a liver cancer tumor in the human body;synthesizing a compound...
A significant dose-dependent antitumor effect was observed for dosages of 200, 400, and 600 kBq/kg of 227Th-trastuzumab but no effect of 400 and 600 kBq/kg 227Th-rituximab (non-tumor binding). No serious delayed bone marrow or normal organ toxicity was observed, but there was a ...
The term “biological sample” encompasses a clinical sample, and also includes cells in culture, cell supernatants, tissue samples, organs, bone marrow, and the like. As used herein, the term “isolated,” in the context of a nucleic acid, is meant to describe a nucleic acid that is in...
fluorescence colonoscopy in 15 patients with a high risk of colorectal neoplasia23. These studies demonstrated the potential of the clinical application of fluorescently labeled probes for cancer diagnosis; however, a long half-life after injection is an issue associated with the intravenous (i.v.) ...