These compounds displayed higher in vitro binding affinities than PCP itself for the PCP-binding site located inside the ion channel on the N-methyl-D-aspartate (NMDA) receptors. Brain distribution studies in mice showed different uptake characteristics between the PCP and TCP analogs, indicating...
RESEARCH DESIGN AND METHODS: Leukostasis was determined by counting the number of fluorescently labeled leukocytes inside retinal vasculature. Expression of ... J Wang,X Xu,MH Elliott,... - 《Diabetes》 被引量: 379发表: 2010年 Mechanisms and sequelae of increased alveolar fluid clearance in hype...
Formation of transition metal–doxorubicin complexes inside liposomes. Biochimica et Biophysica Acta (BBA)-Biomembranes. 2002;1565(1):41–54. Gawne P, Man F, Fonslet J, Radia R, Bordoloi J, Cleveland M, et al. Manganese-52: applications in cell radiolabelling and liposomal nanomedicine PET ...
η 2 is also the hyper-parameter necessary for determining the shape of the distribution π 2. As biologically plausible prior information, we assumed the smoothness of deformation both inside the tissue as well as at its boundary. Specifically, the first spatial derivative of the deformation ...
successfully used for the treatment of depression. SERT first binds a sodium ion, followed by serotonin, and then a chloride ion. The transporter then flips inside the cell, releasing serotonin. A potassium ion binds, and the transporter flips back out, ready to receive another serotonin ...
The nanoparticles internalization was investigated using a light microscope (Olympus BXS1): iron nanoparticles appeared as blue spots inside the cells, while the nucleus appeared red. The cells that exhibit red nucleus and blue intracellular particles were considered PB positive; the percentage of ...
We remark that, for all our methods, we ignored cells that were overlapping the boundary of the image, since we expected that the truncation of the cell due to the image boundary may affect cell morphology causing inconsistencies with cells that are fully contained inside the image. Figure 3 ...
Look Inside Within this Entry Introduction General Requirements for the Application of 99mTc-Radiopharmaceuticals Commercial 99mTc-Radiopharmaceuticals Different Types (Generations) of 99mTc-Radiopharmaceuticals Strategies for the Labeling of Targeting Molecules Developments in the Labeling of Targeting Mo...
This technique was used with success for identifying the deficiency of glucocerebrosidase in Gaucher’s disease, sphingomyelinase in Niemann-Pick disease, and ceramidetrihexosidase in Fabry’s disease(1).Page %P Close Plain text Look Inside Share Share this content on Facebook Share this ...
The inhalation/scavenging unit was designed to maintain the normocapnia of a patient during PET examination by introducing fresh air into the face mask while scavenging the gaseous radioactivity inside of the facemask to the decay tank (tank 2). The unit consisted of a two-hole two-layered fa...