Robert L. Schmidt2, Donald M. Mock3,4, Guohua An1 and Peter Veng-Pedersen1 Background: Prior conclusions that autologous neonatal red blood cells (RBC) have substantially shorter lifespans than allogeneic adult RBCs were not based on direct comparison of autologous neonatal vs. al...
Figure 1: Schematic of imaging genomic loci with quantum dot-labelled TALEs. Within the cytosol of a live cell, the TALEs fused with a short LplA acceptor peptide (LAP) is decorated with trans-cyclooctene and subsequently labelled with tetrazine-conjugated red QD (QD625) via Diels–Alder cyclo...
8,9,10. Dietary fish is a rich source of Omega-3 PUFAs. Omega-3 PUFAs come in several forms but eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been most widely investigated with regard to their cardiovascular benefits. In this regard, the American Heart...
(c) Diagram of the TALE-GFP-fusion protein. (d) Confocal images showing TALE-GFP transiently expressed in living cells (scale bar, 5 mm). (e) Percentage of QD625s (2,000 QD625s in 125 cells) with or without attachment to TALE re-localized to the nucleus. Inset: count and statistics...
Each diagram shows the AUC-ROC score for the specific combination of architecture and selected class. The AUC scores beneath the architecture configurations in the first column are the total AUC-ROC scores for the multiclass evaluation. This class is very heterogeneous (cf. Figure 2f) and thus...
Figure 1.The structure of the microfluidic chip. (A) Schematic diagram of the microfluidic chip. (B) Photograph of a single chip filled with dye. Ideally, when injecting cell suspension from Inlet 2 and cell separation from Inlet 1, red blood cells (RBCs) and nucleated cells are first sepa...
of a booster dose consisting of a subunit vaccine based on the stabilized prefusion SARS-CoV-2 spike protein, MVC-COV1901, or its Beta version, MVC-COV1901-Beta. Participants aged ≥18 and <55 years who received two or three prior doses of MVC-COV1901 vaccines were enrolled and were to...
This suggests that alpha-emitting isotopes have a strong potential to treat metastatic melanoma. Figure 1. Binding of a melanin-specific antibody to melanin in a melanoma tumor and its quality control: (A) A diagram illustrating the process of treating melanoma using a radiolabeled melanin-binding...