Osteoarthritis (OA), a chronic degenerative joint disorder characterized by articular cartilage destruction and osteophyte formation1, is the most common form of arthritis and affects millions of people worldwide2. However, the mechanism underlying OA pathogenesis remains largely elusive, and current treat...
However, its application has been mostly restricted to thin preparations or small samples owing to the difficulty of labeling and observing deep structures in intact specimens. 3D imaging is particularly valuable when analyzing complex structures that are not contained within 2D planes, such as axonal...
During IA, joint pain and inflammation are driven by aberrant proteolysis resulting in the production of inflammatory peptides and the destruction of joint cartilage and bone. Synovial fluid (SF), a proximal fluid which bathes the intrinsic joint structures, is an important reservoir of putative ...
The classification was dependent on the sample data from which it was acquired. The data were collected under the Supervision of the Stroke Coordinator at the Metro-Rehab Hospital. The data was collected in three phases at each posture (flexion or extension) of the knee joint. The healthy and...
These valuable results provide ample evidence of the green electrogeneration of AuNPs on the surface of electrodes and their interaction with loaded aptamers (based on Au-S binding) towards the sensitive and selective monitoring of RIV in human plasma and EBC samples. This bio-assay is an ...
articular cartilage;3D bioprinting;adipose tissue;allogenic hyaline cartilage;knee;osteoarthritis 1. Introduction Knee osteoarthritis (KOA) is the most common progressive disease-causing musculoskeletal disability for patients in the world [1]. Its pathogenesis includes detrimental alterations of the joint, ...