Obtaining frozen sections of bone tissue for intraoperative examination is challenging. To identify the bony edge of resection, orthopaedic oncologists therefore rely on pre-operative X-ray computed tomography or magnetic resonance imaging. However, thes
Osteoarthritis (OA) is characterized by the progressive deterioration of articular cartilage, involving complicated cell-matrix interactions. Systematic investigations of dynamic cellular and matrix changes during OA progression are lacking. In this study, we use label-free two-photon excited fluorescence (...
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However, the detection of cancer is one of the most difficult tasks in cancer pathology. Trained pathologists can analyze complicated tissue structures and detect tumors, but the judgements are subjective, qualitative, and time-consuming, resulting in significant intra- and inter-observer variability. ...
Wound healing is a multifaceted process, and it is balanced by several features, such as the level of damage; it is often linked with the concomitant inflammation process, making wound management a tricky matter. Recently, the development of agents speeding tissue wound repair has been of ...
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If the effectiveness of GD is proven, this will result in new treatment options for advanced bone and soft tissue sarcomas (STS). The aim of this prospective Phase 2 study is to evaluate the efficacy and toxicity of the GD combination in patients with advanced bone sarcomas and STS....
METHODS: In this two-cohort, single-arm, open-label, phase 2 study, we enrolled patients with soft-tissue sarcoma or bone sarcoma from 12 academic centres in the USA that were members of the Sarcoma Alliance for Research through Collaboration (SARC). Patients with soft-tissue sarcoma had to...
Second, we did not evaluate the stool fat soaps and the bone mineral mass, and third, there was a lack of a breastfed reference group. 5. Conclusions In conclusion, the present real-world data highlight that the high sn-2 infant formula may have a beneficial role in improving the ...