Pathology often provides the “gold standard” for disease diagnosis1. Historically, this discipline has relied on the keen eyes of pathologists to make clinical judgments based on visual examinations of stained
The importance of detecting tumour infiltration within surgical specimens during an operation has been recognized for over a century7. Despite our best efforts to deliver precision healthcare to patients with cancer, residual tumour after surgery is a major public health problem in the United States ...
In a shotgun analysis previously performed on whole muscle extracts, the major isoforms of myosin heavy-chain comprise ∼42% of the total spectra (15). Because these major isoforms may hamper identification of other proteins, we decided to precipitate myofibrils at low ionic strength (16, 17)...
Traditional approaches based on Euclidean space embeddings have limitations in capturing the hierarchical structures inherent in medical code data [6]. However, the introduction of hyperbolic embeddings, which represent the hierarchy in hyperbolic space, shows promise in better capturing hierarchical ...
Labeling older adults as vulnerable therefore is only helpful, when it is used to raise awareness of the widespread ageism in society, in this context, especially in the setting of health care, and the negative consequences thereof for older adults....
The appeal of Tanjong Katong stems from its strategic position, nestled near the heart of the city, while still providing a peaceful and relaxed atmosphere. It is the perfect blend of urban convenience and serene living. The URA of Singapore has recently taken on the ambitious task of rejuvenat...
For these samples, it was possible to associate the major part of the false classified image with regions of normal tissue that were all recognized by a pathologist based on retrospective analysis of HE staining of the very same or consecu- tive section. This is the case of samples of ...
‘Piss Artist’ maintain Tomkins vocal style, but finds them crushed into the music like never before. The music is a mix of drum machine, synthesizer, organ and electric piano, all twisted to create a new kind of oppressive atmosphere. Sometimes the music veers into song like structures, ...
One of the major goals in the design of all nonisotopic immunoassays has been to provide a homogeneous system in which no separation of bound and free antibody or antigen is necessary and, therefore, to make these assays technically easier and more rapid. The choice of an enzyme label in ...
The two regions are connected by a highly flexible loop of 22-24 residues called the β-linker. In AMPK crystal structures, a hydrophobic cleft termed the ADaM (Allosteric Drug and Metabolite) site forms between the CBM and the N-lobe of the α-KD, allowing for allosteric activation by ...