Label‐Free and Colorimetric Detection of Influenza A Virus via Receptor‐Mediated Viral Fusion with Plasmonic Vesiclesdoi:10.1002/smll.202305748Moon, YesolLee, SojeongKim, JinyoungPark, GeunseonPark, ChaewonLim, Jong‐WooYeom, MinjooSong, Daesub...
New tuberculosis treatments are needed to address drug resistance, lengthy treatment duration and adverse reactions of available agents. GSK3036656 (ganfeborole) is a first-in-class benzoxaborole inhibiting the Mycobacterium tuberculosis leucyl-tRNA synthetase. Here, in this phase 2a, single-center, ...
An ultrasensitive interferometric method was used to image four virus types with nanoscale optical path-length sensitivity. Pairing these data with fluorescence images for ground truth, we trained semantic segmentation models based on U-Net, a particular type of convolutional neural network. The trained...
Access to the registry key 'HKEY_CLASSES_ROOT\name of the class' is denied. access variable from another function Access Variables in Different Projects in a Solution Accessibility of parent's class fields from child class Accessing a dictionary from another class Accessing a server which requires...
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Thus, broadening CAR recognition to restrain virus escape and sharpening it to target viral reservoirs for elimination could be the key to developing superior anti-HIV-1 CAR-T cells for an HIV-1 cure. Combining with broadly neutralizing antibodies (bNAbs) represents an intriguing strategy to ...
The model is tested on two benchmark datasets of Gpos-mploc and Virus-mPLoc and the maximum average accuracy is achieved over 90%. The model is tested using ML-KNN and Rank-SVM to draw a clear contrast in the result and to restrict the model from overfitting. In order to develop a ...
For example, DOMs have been applied to reveal the molecular pathomechanisms of AP-4 deficiency syndrome, a severe neurological disorder15,16; to char- acterize the function of a lysosomal retrieval pathway17; to quantify translocation events triggered during EGF signalling13; to identify the target...
The quantification of membrane-associated biomolecular interactions is crucial to our understanding of various cellular processes. State-of-the-art single-molecule approaches rely largely on the addition of fluorescent labels, which complicates the quant
We selected an aptamer against a fluorogenic dye called Thioflavin T (ThT). Aptamers are single-stranded DNA that can bind a specific target. We selected the ThT aptamer using graphene oxide assisted SELEX and a low-cost Open qPCR instrument. We optimize