Since not the pixel but the overall diagnosis of the thin sections is of clinical relevance the statistics are provided based on the whole tissue thin section, but not on individual pixels. Figure 1 QCL based IR imaging of whole slice colorectal cancer tissue thin sections. Thin tissue section...
Figure 4 demonstrates several such stain combinations for different pairs of stains. By using these blended stains, aspects of the different stains can be made visible at the same time, which may allow pathologists to more easily view different tissue structures and perform diagnosis. For example,...
Over half of patients in the capsaicin 8% patch groups received the maximum seven capsaicin treatments (167/313 [53.4%]) (Additional file 2: Figure S1 and Additional file 3: Figure S2). Safety Norfolk QOL-DN No deterioration (denoted by a reduction in score) in mean (estimated mean ...
Large Raman datasets acquired from liver tissue were collected and fed into a CNN-based deep learning model to train it to distinguish spectral data of different tissue types. The model was then used to differentiate different pathological types of liver cancer tissues. In addition, the Raman resu...
Damage and degradation of articular cartilage leads to severe pain and loss of mobility. The development of new therapies for cartilage regeneration for monitoring their effect requires further study of cartilage, ideally at a molecular level and in a mi
In the present feasibility study we wanted to demonstrate a subsequent RF that was able to differentiate MSI-H and MSS based on the spectra recognized as tumor cells by the previously presented cancer classifier. Figure 1 Analytical results of label-free digital pathology for colorectal cancer (...
Most infusion-related AEs occurred within the first 3 months of treatment (Figure 1) and nearly two-thirds of patients with infusion-related AEs experienced them dur- ing the first three infusions (Supplementary Table S2 online). The proportions of patients who reported any TEAEs within a ...
Skeletal muscle has a great economic value accounting for up to 50% of the total body weight of an animal and is in the order of 25% of basal metabolic expenditure19,20. This tissue also plays a major role in energy homeostasis. Therefore skeletal muscle (M.longissimus dorsi) was selected...
Characteristics of the tendons Figure1ashows a mouse’s tail after skin removal, and Fig.1bshows the absorption spectrum of tendon in the NIR spectrum. The NIR spectral region (approximately 650–950 nm) or “optical window” has deep photon penetration due to relatively high transparency and...
Water and lipids are key participants in many biological processes, but there are few non-invasive methods that provide quantification of these components in vivo, and none that can isolate and quantify lipids in the blood. Here we develop a new imaging