Briefly, each mouse was fully anesthetized with 2.0% of isoflurane, the scalp was incised, and a metal chamber (Narishige) was affixed to the skull using a light-cured acrylic resin (OA2, Dentkist). An approxim
During the past decades, important advances have been made in better understanding the pathophysiological mechanisms and the signaling pathways involved in the evolution of the ischemic penumbra. Converging evidence suggest that the purine nucleoside adenosine plays a key-role. Adenosine is an important l...
Pre-processing contains skull stripping, image normalization, feature representation, and atlas co-registration. The description of PLA-SOM details the assisted training and calculation of the involved fuzzy membership function. “Method” introduces the PLA-SOM model. “The Experiment: Performance ...
The ischemic volume was imported in Sim4Life v.1.2 and placed in Duke's head model; the correct positioning has been achieved looking at the MRI images and estimating the distance of the ischemia from the skull and other brain structures. We assigned to the ischemic tissue the electric ...
Many carotid dissections can be treated with traditional carotid stents; however, high cervical and skull base dissections, with or without pseudoaneurysms, are more difficult to treat due to the tortuosity of the carotid artery. This location is difficult to access with traditional carotid stents ...
Light can also reveal information on the morphological structure of the brain, however, still very limitedly in human brain imaging, because of strong light scattering and absorption caused by human skull and scalp [9]. In functional monitoring of the human cerebral cortex, optical techniques have...