seniors and the single values of the elderly show gender- and age-specific RIs deviating considerably from the commonly employed RIs. It follows, that the practice of using single gender- and age-independent RIs for platelet counts (e.g. 140–350×109/L) should be abandoned for individuals ...
Remarkably, predominant micelle accumulation in the tumor was demonstrated, indicating the viability of the micellar system for its use with cannabinoids. CBD-loaded poly-ε-caprolactone microparticles, as an alternative delivery system for long-term CBD administration, demonstrated their efficiency in ...
Principal component analysis confirmed the association between "repair" gene expression and EVLP duration, with maximum values after 12 hours (Fig. 2). Conclusions: We defined a gene set for quantification of ALI that can be used for molecular monitoring of tissue repair during EVLP and thus as...
Necrosis (+/-), vascular changes [none-hypertrophy-microvascular proliferation (MVP)], and Ki67 values by IHC were noted. Statistical analysis was performed to identify relationships between features of progression (MRI, histology, Ki-67 indices), genetic alterations and clinical outcomes. Results: ...
All four cell lines with EC50 values of In vivo(体内研究) When ABT-263 is administered at 100 mg/kg/day in the H345 xenograft model, significant antitumor efficacy is observed with 80% TGI and 20% of treated tumors indicating at least a 50% reduction in tumor volume. Oral ...
Normal tissue gene expression values (RNA-Seq) are used as the model baseline, and the rates of the molecular interactions are optimized to predict 27 tumor gene expression values. The percent error for each gene expression value is calculated to compare simulated and patient tumor data. Results...
P-values < 0.05 were considered significant. The revised diagnoses were then reviewed by an oncologist to determine whether changes in therapy would result from the change in diagnosis. Diagnostic changes were grouped as either major (resulting in a change in therapy) or minor (having no impact ...
By contrast, most Ki-67+ glomerular epithelial cells 350A were strongly claudin+, indicating predominant expansion of the parietal compartment. Claudin+ cells typically extended out from Bowman's capsule to bridge and overlie the glomerular tuft in acute collapse and more chronic NOS lesions, often...
1328 Metabolic and Immunologic Characteristics of HPV+ oropharyngeal Cancers Indicating an Adaptive Mechanism to Increased Tumor Immunogenicity R Krupar, K Robold, M Kreutz, F Hofstaedter, AK Bosserhoff. University of Regensburg, Regensburg, Germany. Background: Lymphopeithelial regions are predilection...
These patients are likely to present with markedly increased Cr values, and often with severe hematuria or proteinuria. Recent discoveries of autoantibodies against lysosomal-associated membrane protein-2, a previously recognized ANCA antigen that is abundantly expressed on endothelial cells, suggests that...