Many laboratory experiments require the use of laboratory animals of varying sizes and types, such as mice and rats. The laboratory animals are kept in isolated environments, known as metabolic cage units, wherein their intake of food and water is carefully measured and controlled. Additionally, ...
Determination of acute toxicity in mammals (e.g. rats or mice) is one of the most important tasks for the safety evaluation of drug candidates. Because in vivo assays for oral acute toxicity in mammals are time-consuming and costly, there is thus an urgent need to develop in silico ...
An intraperitoneal dose of 5 mg/kg of reserpine was administered to batches of 5 male rats CF1 weighing an average of 300 g. 30 minutes later, the rectal temperature was determined and then a dose of the compound to be tested was given by oral route, except to the control animals. The...
Brains from three 18 months old female rats (two transgenic TgF-344 AD animals and one wild type control) obtained from the local breeding colony at Faculty of Medicine in Pilsen, Charles University, were used to collect the data. All protocols followed in this study were approved by the Eth...
Lipidized PrRP Analog Exhibits Strong Anti-Obesity and Antidiabetic Properties in Old WKY Rats with Obesity and Glucose Intolerance. Mráziková L, Hojná S et al. Nutrients 2023;15(2) https://doi.org/10.3390/nu15020280 Monoisotopic silver nanoparticles-based mass spectrometry imaging of huma...
RatsConnective TissueMyocardiumMicroscopy, Electron, ScanningPapillary MusclesChickensCricetinaeAn extensive collagen skeleton in the myocardium is clearly demonstrable by scanning electron microscopy. This system ...
Hsu C, et al. Prenatal Exposure of Testosterone Prevents SDN-POA Neurons of Postnatal Male Rats. J Neurophysiol86:2374-2380, 2001. Ghaffarpasand F, Afshariani R. 口服锌治疗对男性患者性激素水平的影响。血液透析。Ren Fail. 2...
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ANNUAL MEETING ABSTRACTS In the comparison groups, 23/23(100%) of the IgG4-RSD showed moderate to marked increase in IgG4+ cells, 6/24(25%) cases of pauci-immune GN, 1/14(7%) Sjogren TIN, and 0/17(0%) TIN in patients with a history of pancreatitis, 1/2(50%) with ...
D-Iditol is a chromatographic stationary phase that is used for hydrophilic interaction chromatography. It is a polymer of 1,2-diols and long-chain fatty acids. D-Iditol has been shown to have long-term toxicity in rats and has been shown to be carcinogenic in mice. This substance binds ...