The rates of reaction of 2-, 3- and 4-chloropyridine N-oxides towards 1 M piperidine in methanol have been measured conductimetrically. Apparent unimolecular rate constants at 80掳C are respectively 3,70.10 4 , 1,04.10 7 and 1,02.10 4 sec 1 . The reactivity sequence 2 > 4 >> 3 is...
The mechanism of activated nucleophilic substitution in the aromatic series (S. N. A.*) can be integrated in the general scheme of S. N. synchronous mechanisms. The relative order of mobilities of the halogens in S. N. A. * type reactions, wich varies with the nucleophilic activity of ...
This result agrees with the proposal that preferential equatorial attack of a nucleophile is caused by conformational factors related to a steroid non-steroid conformation equilibrium in thecis-isomers.[Journal Translation]C. AgamiT. RizkR. DurandP. Genestecanadian journal of chemistry...
La substitution nucléophile activée en série aromatique II.—Effet polaire des groupements alcoyle-Réaction d'échange bromo-iode dans une série de 1-alcoyl-4-bromo-3,5-dinitro-benzènes Mlle A. Pinguair, P. J.C Fierens†, A. Frennet and A. Halleux Article first published onlin...
The calculated energy differences between the two tautomers agrees with the experiment in the case of oxygen and nitrogen derivatives, but in the case of thioamides the real situation lies between the sp and spd approximation. To understand the origin of the differences between the equilibrium ...