Downregulation of nitric oxide by electroacupuncture against hypoxicischemic brain damage in rats via nuclear factorκB/neuronal nitric oxide synthase. The activator, S-adenosyl-L-methionine and the inhibitor, hydroxylamine of cystathionine-β-synthase (CBS), aggravated and remitted the hypoxic damage in...
Melatonin and S-adenosyl- l-methionine (SAMe) prevent oxidative stress and tissue dysfunction in obstructive jaundice (OJ). Lipid peroxidation is exacerbated in the presence of trace amounts of iron (Fe). The study investigated the regulation by melatonin and SAMe the induction of oxidative stress...
the C3′-deoxygenation of aminoglycoside antibiotics Fumitaka Kudo, Takahiro Tokumitsu and Tadashi Eguchi A radical S-adenosyl-L-methionine dehydratase AprD4 and an NADPH-dependent reductase AprD3 are responsible for the C3′-deoxygenation of pseudodisaccharide paromamine in the biosynthesis of apramycin...
W., Ferguson, S. J. & Hajdu, J. The anatomy of a bifunctional enzyme: structural basis for reduction of oxygen to water and synthesis of nitric oxide by cytochrome cd1. Cell 81, 369–377 (1995). Article CAS PubMed Google Scholar Carlson, C. A. & Ingraham, J. L. Comparison of ...
inducible nitric oxide synthase;JNK,c-Jun N-terminal kinase;MAT,methionine adenosyltransferase;MDA,malondialdehyde; 3-NT, 3-nitrotyro-sine; PNP, p-nitrophenol; SAH, S-adenosyl homocysteine; Sal, saline; SAM,S-adenosyl-L-methionine; TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP nick-end...
At temperatures of 44°C and higher, MetA completely aggregates and is no longer found in the soluble protein fraction, thus limiting growth [9]. The chemical chaperone trimethylamine oxide reduces insoluble MetA accumulation and improves E. coli growth at elevated temperatures [9]. It has been...
At temperatures of 44°C and higher, MetA completely aggregates and is no longer found in the soluble protein fraction, thus limiting growth [9]. The chemical chaperone trimethylamine oxide reduces insoluble MetA accumulation and improves E. coli growth at elevated temperatures [9]. It has been...