505的L-谷氨酰胺脱羧酶立体选择性地将D,L-谷氨酰胺中L型对映体降解为4-氨基-丁酰胺,分离得到D-谷氨酰胺。6) glutaminase [ɡlu'tæmineis] 谷氨酰胺酶 1. Identification of A Strain with High Ability of Producing Glutaminase and Study of Enzymatic Characterization; 一株高产谷氨酰胺酶菌株的鉴...
谷氨酰胺酶( glutaminase )是酰胺酶的一种, 是一种能够将谷氨酰胺催化分解为谷氨酸和氨的生物酶,对其抑制有望用于癌症的治疗,起到独到的作用。研究发现,PEG-PLA聚合物可以提高6-重氮-5-氧代-_L-亮氨酸(DON)的体内抗癌活性。DON是L谷氨酰胺的拮抗剂,它能够阻断与L-谷氨酰胺相关的生化反应,谷氨酰胺可以抑制...
Various fungal strains have been screened for L- glutaminase synthesis. Aspergillus oryzae NRRL 32657 proved to be the highest producer (24.19 U.ml-1) with the largest pink zone diameter (8 mm). Production of L- glutaminase (E.C. 3.5.1.2. L-glutamine amidohydrolase) by A. oryzae in batch...
Pseudomonas ovalis produces L-glutaminase and L-asparaginase activities simultaneously upon induction by L-glutamine or L-asparagin in the growth medium. Both activities are confined to the cell during active growth and are not released into the medium. The apparent K M values are 1.4 × 10 -2...
Assay of L-glutaminase L-glutaminase activity was determined using L-glutamine as substrate according to Imada et al. [18] method and the released ammonia was measured by using Nesseler’s reagent. Purification of L-asparaginase from Streptomyces brollosae NEAE-115 The crude enzyme extract used ...
谷氨酰胺酶( glutaminase )是酰胺酶的一种, 是一种能够将谷氨酰胺催化分解为谷氨酸和氨的生物酶,对其抑制有望用于癌症的治疗,起到独到的作用。研究发现,PEG-PLA聚合物可以提高6-重氮-5-氧代-_L-亮氨酸(DON)的体内抗癌活性。DON是L谷氨酰胺的拮抗剂,它能够阻断与L-谷氨酰胺相关的生化反应,谷氨酰胺可以抑制...
Maximizing the production of L Glutaminase 来自 Semantic Scholar 喜欢 0 阅读量: 14 作者: T Satish 摘要: The paper explains the expediency of developing an explicit rule of monetary policy for the economy of Ukraine. It studies the stages of its development, proving the expediency of ...
Conclusion: This study provides the first potential of glutaminase-free l-asparaginase production from the marine bacterium Bacillus velezensis as a prospect anticancer pharmaceutical agent for two different breast cancer cell lines.How to cite: Mostafa Y, Alrumman S, Alamri S, et al. Enhanced ...
To examine L-asparaginase (ASNase) and/or L-glutaminase (GLNase) activities in marine bacterial strains, modified asparaginase dextrose salt agar (MADS) was used to culture the bacteria [17]. The composition of MADS was as follows: 2.0 g glucose, 10.0 g L-asparagine monohydrate (Sigma-Aldric...