1999) and the arginine homologue asymmetric dimethy- larginine (ADMA; Vallance et al. 1992; Lin et al. 2002; Kielstein et al. 2003). Inhibition of NO synthesis by the lat- ter is counterbalanced by its catabolism by the enzyme dimethylarginine dimethylaminohydrolase, which is partic- ul...
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is related to the DNA damage response100,101, were downregulated. The gene for histone-arginine methyltransferase CARMER was also downregulated. This methyltransferase is important for the modulation of the ecdysone-induced expression of cell death genes102. In addition, peroxiredoxin 6, which protects...
4,8,9 Currently, there are various types of siRNA delivery platforms, ranging from viral to non-viral vectors, each having their pros and cons when it comes to mitigating the obstacles described above, with the non-viral vectors encompassing technologies such as lipids, polymers, aptamers, and...
albus) in food and human health and to balance the pros and cons. Nutritional and anti-nutritional components of L. albus seeds and possible contaminants of lupine seeds are examined. The potential health benefits of lupine (seeds), including energy metabolism, cardiovascular diseases, hypertension,...
In the past several years, attention has been turned to evaluation of four specialized nutrients and the use of other substrates as pharmacologic agents. Pertinent laboratory and clinical data were reviewed to present the pros and cons for each nutritive substrate. Medium-chain fatty acids, branched...