Kupffer cells (KC) are found in the sinusoid lumen. (b) Between the hepatocytes and discontinuous, fenestrated sinus endothelial cells (SE), the space of Disse (SD) is located. Here, hepatic stellate cells (SC), also named Ito cells, are situ- ated. Kupffer cells are, firmly or loosely...
Kupffer cells and pit cells are not effective in the defense against experi- mentally induced colon carcinoma metastasis in rat liver. In: Wisse E, Knook DL, Balabund C, eds. Cells of the Hepatic Sinusoid. Leiden: Kupffer Cell Foundation, 1997:457-459....
Pit cells are found in the sinusoidal lumen, adhering to the endothelial cell lining and occasionally to Kupffer cells. These are a special, liver-specific, population of large granular sinusoidal lymphocytes (Bouwens and Wisse, 1988) that are responsible for natural killer (NK) activity in the ...
These cells named honouring the German physicianKupfferare found on the lumen side of endothelial cells of liver blood vessels; they become activated during infections, e.g., with malarial parasites and react by catching floating sporozoites. They also eliminate other material from blood and are nam...
Watch complete video answer for “Kupffer's cells are” of Biology Class 12th. Get FREE solutions to all questions from chapter DIGESTION AND ABSORPTION .
ERMAP activates phagocytosis in Kupffer cells to restrict liver metastases Kupffer cells, hepatic resident macrophages, are the first line of defense against liver metastases by engulfing disseminated malignant cells. We found that ERMAP expressed on tumor cells binds to galectin-9 and dectin-2 on ...
Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia. Related to Kupffer cells: Space of DisseKupf·fer cells (kūp'fĕr), phagocytic cells of the mononuclear phagocyte series found on the luminal surface of the hepatic sinusoids. Synonym(s): stellate cells of liver Farlex ...
Greene, J. D. & Hill, R. L. ( 1993 ) Isolation, detection and ligand-binding specificity of a lectin uniquely found on rat Kupffer cells , in Lectins and glycobiology ( Gabius, H.-J. & Gabius, S. , eds) pp. 55 – 64 , Springer Publ. Co., Heidelberg ....
Kupffer cells, the liver tissue resident macrophages, are critical in the detection and clearance of cancer cells. However, the molecular mechanisms underlying their detection and phagocytosis of cancer cells are still unclear. Using in vivo genome-wide CRISPR-Cas9 knockout screening, we found that ...
1ivertransplantation(OLT)inSpragueDawley(SD)rats,observetheinductionof immuneto[erancewithorwithoutpretreatmentofgadoliniumchloride(GdCh)which canblockphagocytesis ofKupffercells(KCs),andinvestigatetheeffectofGdCL3 ontheinductionof l:verallografttoleranceinSDrats;(2)todetectexpression ...