Between 2012-2013, the largest public tertiary-care hospital in Quito (Ecuador) reported an outbreak of KPC-producing bacteria with more than 800 cases. We developed a molecular epidemiological approach to analyse the clonality of K. pneumoniae isolates recovered from selected hospital services and ...
The Wzc protein is considered as the major regulator of CPS production in gram-negative bacteria, but the specific mechanism driving this process remains unclear [41]. Further research is needed to elucidate the intrinsic mechanism by which Wzc mutations lead to bacterial hypermucoviscosity. ...
Carbapenem susceptibilities and non-susceptibility concordance to different carbapenems amongst clinically important Gram-negative bacteria isolated from i... Outbreak of Klebsiella pneumoniae carbapenemase-2-producing K. pneumoniae sequence type 11 in Taiwan in 2011. Antimicrob Agents Chemother 2012;56:5016...
The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis. 2009;9(4):228–36. Article CAS Google Scholar Woodford N, Tierno PM Jr, Young K, Tysall L, Palepou MF, Ward E, et al. Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing ...
Since 2003, patients hospitalized in the surgical ward of our hospital have been systematically screened on admission and weekly thereafter for intestinal carriage of bacteria producing extended-spectrum β-lactamases (ESBLs) and carbapenemases by plating rectal swabs on Drigalski agar containing 0.5 mg...
The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis. 2009;9(4):228–36. https://doi.org/10.1016/S1473-3099(09)70054-4. Article CAS PubMed Google Scholar Yigit H, Queenan AM, Anderson GJ, et al. Novel carbapenem-hydrolyzing beta-lactamase, KPC-1,...
13 Martino MD(Koga PC)Pasternak J,et al Evaluation of a new rapid test for carbapenemase detection in carbapenem resistant Enter鄄obacteriaceae[J] J Microbiol Methods(2)15( 115)2,-2114 Chen LF,Anderson DJ,Paterson DL Overview of the epidemiology and the threat of Klebsiella pneumonia carbapen...
The emergence of Klebsiella pneumoniae carbapenemases (KPCs) producing bacteria has become a significant global public health challenge while the optimal treatment remains undefined. We performed a systematic review of published studies and reports of tr
Co-colonization by multidrug-resistant bacteria in two Greek intensive care units [J]. Eur J Clin Microbiol Infect Dis, 2015, 34 (10): 1947-1955. DOI: 10.1007/s10096-015-2436-4. [16] Tuon FF,...
The following data were collected: site of KPC-KP culture; present or past history of cultures positive with other MDROs, including vancomycin-resistant enterococci, ESBL-producing Gram-negative bacteria and methicillin-resistant Staphylococcus aureus; and microbiological response to therapy. The presence ...