What is KSP in chemistry? The solubility product constant, Ksp, is the equilibrium constant for a solid substance dissolving in an aqueous solution. It represents the level at which a solute dissolves in solution. The more soluble a substance is, the higher the Ksp value it has.Similar...
Calpain-mediated integrin deregulation as a novel mode of action for the anticancer gallium compound KP46. Mol Cancer Ther. 2014;13:2436–49. 18. Wang ZX, Yang JS, Pan X, Wang JR, Li J, Yin YM, De W. Functional and biological analysis of Bcl-xL expression in human osteosarcoma. ...
The TTPA molecule consists of 192 amino acid residues; in the electron density map, however, all of the chains have an additional nine expression-plasmid-derived amino acids at the N-terminus (numbered −8 to 0). In addition, not all of the main chain residues are visible in the ...
unbound CNS drug concentrations are currently widening the perspectives and usage of the Kp,uu,brainconcept (112,113,114,115,116). Whilst this introduction above provides a high-level summary of the development of Kp,uu,brainconcepts and methodology, there are little real world ‘data’ available...
These results show that either expression of KP4 under the control of a maize ubiquitin promoter and/or the effects of the toxin may have pleiotropic effects on the expression of pathogen-related genes, either increasing or decreasing their transcript abundance depending of the gene. However, it ...
No-carrier-added (“tracer level”) [68Ga]KP46 and [67Ga]KP46 were produced by mixing 8-hydroxyquinoline with, respectively,68Ga- or67Ga-chloride in acetate buffer, resulting in efficient chelation, to form a radioactive lipophilic complex. The radioactive product was purified by elution with...
The same theory shows that the critical density should decrease with increasing non-additivity, reaching a value ρcd3≈0.08 for Δ=1, in broad agreement with the predictions of other theoretical approaches and the results of other simulations16. An expression for the first-order correction to ...
of the invention, the dihydroxyacid dehydratase derived from the genus Pichia, Escherichia, or Corynebacterium, such as a dihyroxyacid dehydratase is a Pichia stipitis dihydroxyacid dehydratase ILV3 gene product or an ILV3 gene product that has been modified to optimize cytoplasmic expression.Another...