We demonstrated that ATF4 directly governs this process at the transcriptional level. Mechanistically, importin subunit beta-1 (KPNB1) plays a crucial role in facilitating ATF4 nuclear translocation via its nuclear localization signal (NLS), subsequently activating the BNIP3 pathway and promoting odonto...
J Biol Chem. 2011;286(50):43383–93. Article PubMed PubMed Central CAS Google Scholar Du W, Zhu J, Zeng Y, Liu T, Zhang Y, Cai T, et al. KPNB1-mediated nuclear translocation of PD-L1 promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signaling pathway. ...
To prospectively evaluate our proposed strategy, we assessed the influence of pH and temperature on enzyme-substrate reactions by creating two datasets. These contained enzyme sequences, substrate structures, and corresponding pH or temperature values and were sourced from UniProt and PubChem6,31. The...
Given the pivotal role of mitophagy in the differentiation of DPSCs, the level of mitophagy in DPSCs treated with either growth medium or odontogenic differentiation medium for 3 days was assessed via fluorescence staining. The results indicated that DPSCs treated with OM presented higher levels of m...
K. Watanabe, A.P. Praseuth, C.C. Wang A comprehensive and engaging overview of the type III family of polyketide synthases Curr. Opin. Chem. Biol., 11 (2007), pp. 279-286 View PDFView articleView in ScopusGoogle Scholar [23] M. Mohammadi, S. Srivastava, J.C. Hall, N.N.V. Ka...
Briefly, the luciferase reporter plasmids (TNF-α-wt and TNF-α-mt, DGCR8-wt and DGCR8-mt, nestin-wt and nestin-mt) were constructed by Gene-Chem. GSCs were seeded into 96-well plates at a density of 5 × 103 cells per well and transfected with these plasmids for 48 h. Then...
protein A agarose, protein G agarose (Roche Diagnositics, Indianapolis, USA), bafilomycin A1 (Baf-A1), ivermectin (IVM), MG132, z-VAD-FMK (Selleck, Shanghai, China), Act D, chloroquine diphosphate (CQ), z-DEVD-FMK, z-IETD-FMK (Medchem Express, Monmouth Junction, USA), human recomb...
(a) the colony count (CFU/ml); (b) LIVE/DEAD BacLight Bacterial Viability Kit with live to dead cells ratio at fluorescence 530/630 nm; (c) the crystal violet staining and the level of absorbance at 595 nm.P-value < 0.001 indicated as two asterisks, andP-value between 0.01 and...
Electronic structure and fundamental absorption edges of KPb2Br5, K0.5Rb0.5Pb2Br5 and RbPb2Br5 single crystals. J. Phys. Chem. Sol., submitted.Tarasova A.Yu., Isaenko L.I., Kesler V.G., Pashkov V.M., Yelisseyev A.P., Denysyuk N.M., Khyzhun O.Yu. Electronic structure and ...
Mykrolis QuickChange SH4P009E03 AT Chemlock Filter,0.2um20",SP6002-6920,new~3404 Mykrolis QuickChange ATX QCCGATX01 Cartridge Chemical Filter,0.2um10",unuse~3394 Mykrolis Guardian HPX20" HPX 0.2um TEV 20"L,GHPG02P01,SP6002-6919,Unused~3392 ...