事实上,对照先前描述的循环和扁桃体 NK、ILC1 和 ILC3 细胞特征[25],对不同的 TI-NK 细胞转录组进行的 GSEA 分析进一步证实了 CD16+ TI-NK 细胞与循环 CD56dim NK 细胞、CD16- CD103+ TI-NK 细胞与扁桃体 ILC1 之间的相...
然后,我们确定了编码 NK 受体的基因(图1B)在整合对象的不同细胞类型中的表达。与最近的一项研究一致,我们发现抑制性受体 CLEC5B(也称为 CD161)(由 KLRB1 编码)、CLEC15A(由 KLRG1 编码)和 NKG2A/CD94(由 KLRC1/KLRD1 编码)...
蛋白别名:CD159 antigen-like family member C; CD159c; killer cell lectin-like receptor subfamily C, member 2; killer cell lectin-like receptor subfamily C, member 4; natual killer cell group 2-F; NK cell receptor C; NK cell receptor F; NKG2-C type II integral membrane protein; NKG2-C...
The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. (provided by RefSeq) Long Name ...
NKG2C NK cells are potent antiviral effector cells, potentially limiting the extent of SARS-CoV-2 infections. NKG2C is an activating NK cell receptor encoded by the KLRC2 gene, which binds to HLA-E on infected cells leading to NK cell activation. Heterozygous or homozygous KLRC2 deletion (...
蛋白别名:CD159 antigen-like family member C; CD159c; killer cell lectin-like receptor subfamily C, member 2; killer cell lectin-like receptor subfamily C, member 4; natual killer cell group 2-F; NK cell receptor C; NK cell receptor F; NKG2-C type II integral membrane protein; NKG2-C...
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been...
The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. 仅用于科研。不用于诊断过程。未经明确...
(extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-...