This gene encodes a member of the Kruppel-like family of transcription factors. The zinc finger protein is a transcriptional activator, and functions as a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene, some of which are implicated in carcinog...
别名Kruppel-like factor 6; B cell derived protein 1; BCD1; COPEB; Core promoter element-binding protein; CPBP; GC rich sites binding factor GBF; Krueppel-like factor 6; Proto-oncogene BCD1; Transcription factor Zf9; Zf9; CBA1; DKFZp686N0199; GBF; PAC1; ST12; KLF6_HUMAN. ...
Dysregulation of the NF-κB transcription factor occurs in many cancer types. Krüppel-like family of transcription factors (KLFs) regulate the expression of genes involved in cell proliferation, differentiation and survival. Here, we report a new mechanism of NF-κB activation in glioblastoma ...
别 名 Kruppel-like factor 6; B cell derived protein 1; BCD1; COPEB; Core promoter element-binding protein; CPBP; GC rich sites binding factor GBF; Krueppel-like factor 6; Proto-oncogene BCD1; Transcription factor Zf9; Zf9; CBA1; DKFZp686N0199; GBF; PAC1; ST12; KLF6_HUMAN. 浓 ...
转染抑癌基因KLF6抗体 KLF6 来源 Rabbit 规格 0.1ml 0.2ml 价格 询价 产品介绍 别名Kruppel-like factor 6; B cell derived protein 1; BCD1; COPEB; Core promoter element-binding protein; CPBP; GC rich sites binding factor GBF; Krueppel-like factor 6; Proto-oncogene BCD1; Transcription factor ...
KLF6基因是普遍表达的核转录调控因子,又称为Zf9(zine finger factor 9)、CPBP(core promoter element-binding protein)[2]。最初是从人的胎盘组织和鼠的肝星形细胞中克隆出来,定位于人类染色体10P15。野生型KLF6基因全长约7kb,含有4个外显子,分别为218、574、124、525bp,突变常发生在第2、3外显子,mRNA长138...
别名Kruppel-like factor 6; B cell derived protein 1; BCD1; COPEB; Core promoter element-binding protein; CPBP; GC rich sites binding factor GBF; Krueppel-like factor 6; Proto-oncogene BCD1; Transcription factor Zf9; Zf9; CBA1; DKFZp686N0199; GBF; PAC1; ST12; KLF6_HUMAN. ...
Kruppel like factor 6 (KLF6) is a ubiquitously expressed zinc finger transcription factor that is deregulated in multiple cancers through loss of heterozygosity (LOH) and/or inactivating somatic mutation. We analyzed the potential role of the KLF6 tumor suppressor gene in 41 patients who had HCC ...
Kruppel-like factor 6 (KLF6) is a zinc finger transcription factor of unknown function. Here, we show that the KLF6 gene is mutated in a subset of human pr... Narla,Goutham,Heath,... - 《Science》 被引量: 966发表: 2001年 Krüppel-Like Factor 6 Is Frequently Down-Regulated and Induces...
Cell and tissue specific expression of human Krüppel-like transcription factors in human ocular surface. PURPOSE: The ocular surface, composed of the conjunctiva and the cornea, is essential for vision. Its integrity depends on numerous molecular and cellular ... F Chiambaretta,FD Graeve,G Tur...