Klebsiella variicolaa newly defined species in 2004 was cultured from a range of plants including banana, rice, sugar cane, and maize and from the hospital environment.Calymmatobacterium granulomatisproducesgranulomatous lesionsin humans and was renamed asKlebsiella granulomatisbased on 16SrRNA analysis...
Phage therapy has gained world- wide attention with being carried out as an alternative treatment for refractory infections including those due to K. pneumonia [4]. In addition to good safety, phage therapy has achieved positive outcomes in some cases with complicated UTI, fracture-related ...
variicola) or K. oxytoca together with E. cloacae, one of the species may be overlooked leading to misdiagnosis of originally polymicrobial UTI. Additionally, according to European urinalysis guidelines [66], mixed bacterial growth is often regarded as contamination by patient's flora, being ...
Multidrug-resistant (MDR) bacteria pose a significant challenge to the treatment of infectious diseases. Of particular concern are members of the Klebsiella pneumoniae species complex (KpSC), which are frequently associated with hospital-acquired infecti
phylogenetic structure, theK. pneumoniaespp., the complex is divided into seven major phylogenetic groups: Kp1 (K. pneumoniaesubsp.pneumoniaeorK. pneumoniae sensu stricto); Kp2 (K. quasipneumoniaesubsp.quasipneumoniae); Kp3 (K. variicolasubsp.variicola); Kp4 (K. quasipneumoniaesubsp.similipneumoniae...
Wastewater treatment plants receive ARGs and ARBs from domestic and clinical sources; however, the removal of these and most antibiotics is not entirely effective. Consequently, despite reducing the bacterial abundance in effluents, wastewater treatment, even when following legal recommendations, still res...
For instance, treatment with AKB-4924 prevented internalization of E. coli by uroepithelial cells. K. pneumoniae is not readily internalized by epithelial cells due to its capsule; therefore, preventing the uptake of bacteria through HIF-1α stabilization may not be an effective therapy against K...
variicola, n = 70 [3%]) (Fig. 1A). Principal-component analysis (PCA) based on the 5,650 accessory genes also distinguished the 2,193 genomes into four groups with only a small number of shared genes (Fig. S2). The majority contained four intrinsic ARGs (blaSHV, fosA, oqxA, ...
variicola, respectively. The organisms came from a variety of samples: blood (n = 25, 29.4%), pus (n = 2, 2.4%), sputum (n = 9, 10.6%), urine (n = 37, 43.5%), and wound swabs (n = 12, 14.1%) (Figure 1; Table 1)....