Knowledge of local antibiotic susceptibility rates is essential for strengthening antimicrobial stewardship programmes.DASH to Protect Antibiotics(https://dashuti.com/) is promoting the dissemination of focused local antibiograms in community UTI. This study maps the susceptibility profile ofKlebsiella ...
under heavyantibioticusage,multiple drug resistancehas been increasingly observed inKp.Kpstrains harbouring extended spectrum beta-lactamases (ESBL) and more recently metallocarbapenemase, conferring resistance to many of the antibiotics available, have been described in many parts of the world. These mult...
An important risk to managing infectious illnesses is antibiotic resistance in bacterial pathogens [6]. There is a great need for novel antimicrobial medicines, but the development of new classes of antibiotics has stalled recently owing to demands of cost and market viability. There have been sever...
With the growing concern over antibiotic resistance, interest in phage therapy as a possible solution to the problem that is expanding rapidly. Phage therapy is being used to control pathogenic bacterial infections especially multiple antibiotic-resistant bacterial infections and as potential anti-inflammato...
Antibiotic resistance rates in hypervirulent Klebsiella pneumoniae strains: a systematic review and meta-analysis. J Global Antimicrob Resist. 2024. Poirel L, Potron A, Nordmann P. OXA-48-like carbapenemases: the phantom menace. J Antimicrob Chemother. 2012;67(7):1597–606. Article CAS PubMed ...
Thapa et al Dovepress Antibiotics are the empirical choice of treatment to counter such pathogenic strains of bacteria. However, despite the advent of effective antibiotic therapy, bacteria are constantly evolving noble mechanisms to evade the treatment regimen in question, giving rise to the global ...
pneumoniae in patients of UTI of tertiary care hospital, Bhopal M.P.; to record the antibiogram and probable drug of choice for K. pneumoniae considering the antibiotic susceptibility testing, cost, side effects and many other factors.Kumar...
Conclusions: It has been shown in this case that UTI with the aetiology of K. pneumoniae could be treated on an outpatient basis with high doses of amoxicillin in combination with standard doses of clavulanic acid followed by prolonged antibiotic prophylaxis....
Multidrug-resistant Enterobacteriaceae is one of many examples of rapidly evolving resistance to antibiotics being reported worldwide.40–43 Fosfomycin has long been the antibiotic of choice for treating MDR Enterobacteriaceae infections (including those involving ESBL and carbapenemase producers), but ...
Multidrug-resistant (MDR)/Pandrug-resistant (PDR) bacteria causing UTIs are very challenging to conventional antibiotic therapy. However, bacteriophages may be a promising alternative as they easily disrupt the biofilm and act on receptors unrelated to antibiotic resistance mechanisms. This preclinical ...