K. pneumoniaeisolated was susceptible to most antimicrobial agents except for ampicillin. Only 2 strains ofK. pneumoniaeshowed ESBL production, which were both blood-isolated. These 2 KP-PLA patients were >70 years of age, diabetic and had a history of hypertension. During hospitalization, they de...
Moderate Resistance: there was moderate resistance to cephalosporins such as ceftriaxone and ceftazidime, highlighting the presence of extended-spectrum β-lactamase (ESBL)-producing strains. Low Resistance: the lowest resistance rates were observed for carbapenems like meropenem and imipenem, indicating the...
ESBLs can potentially be inhibited by clavulanate, but they have an in vivo therapeutic effect only for urinary tract infections (UTIs). Inhibitor-resistant TEMs (IRTs) and inhibitor-resistant SHVs (IRSs), as well as carbapenemases called K. pneumoniae carbapenemases (KPCs), are classified in ...
Several studies have reported the presence of multidrug-resistance (MDR), fluoroquinolone-resistance and extended-spectrum β-lactamase (ESBL)-producing K. pneumoniae in both clinical [43,62,63] and non-clinical isolates [64] in Malaysia. The aquatic-borne K. pneumoniae isolates from the Matang ...