网络释义 1. 小鼠 ...对高蛋氨酸喂养诱发的高同型半胱氨酸血症的2型糖尿病小鼠(Kkay mice)血清tHcy水平及糖尿病肾脏病变的影响。方法:给 ... … wiki.cnki.com.cn|基于 1 个网页
代谢组学尿液KKay小鼠2型糖尿病Objective: To investigate rosiglitazone's mechanism in treating type 2 diabetes mellitus (T2DM) in KKay mice via urinary metabonomics. Methods: KKay mice were chosen as the model animals and given with rosiglitazone at a dose of 2 mg·kg-1 by intragastric ...
This study aimed to study astragaloside effect on TGF-β1, SMAD2/3, and α-SMA expression in the kidney tissue of diabetic KKAy mice, to reveal its potential impact on renal interstitial fibrosis. 20 type II diabetic KKAy mice were randomly equally divided into model group and astragaloside ...
Coleman DL. Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia. 1978;14(3):141-148. Winzell MS, Ahrén B. The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes. Diabetes. 2004...
Angelica polysaccharides (AP) have numerous benefits in relieving type 2 diabetes (T2D). However, the underlying mechanisms have yet to be fully understood. Recent many reports have suggested that altering gut microbiota can have adverse effects on the h
were determined in KKAy mice. The primary goal was to determine the mechanism by which BKN relieves diuresis, thirst and dermal pruritis in diabetics. MATERIALS AND METHODS Materials. BKN extract powder was donated by Tsumura & Co. (Tokyo, Japan). A high-capacity cDNA synthesis kit was purchas...
As insulin resistance is closely associated with metabolic syndrome, this study is aimed to elucidate how GluOC regulates glucose and lipid metabolism in KKAy mice, an animal model displaying obese, hyperglycemia, hyperinsulinemia, insulin resistance, and hepatic steatosis. GluOC (3, 30 ng/g per...
Ina K,Kitamura H,Okeda T,et al.Vascular cell adhesion molecule-1 expression in the renal interstitium of diabetic KKAy mice.Diabetes Research and Clinical Practice. 1999Ina K,Kitamura H,Okeda T. Vascular cell adhesion molecule-1 expression in the renal interstitum of diabetic KKAY mice[J]....
effect of the traditional Chinese medicine decoction Zishen pill on diabetic mice and the mechanism of the drug on hepatic insulin resistance.Methods 21KKay mice were randomly divided into Zishen pill high⁃dosage group and Zishen pill low⁃dosage group,a model group,and 7C57mice as the ...
Effect of insulin intraperitoneal injection combined with dietary intervention on blood glucose regulation in KKAy mice with spontaneous type 2 diabetes 引用 收藏 分享 摘要 目的研究胰岛素腹腔注射配合饮食干预对自发性2型糖尿病KKAy小鼠血糖调控的效果。方法建立2型糖尿病动物模型,选取健康C57BL/6J小鼠作为正常...