Chemical Kinetics In subject area: Neuroscience Chemical kinetics refers to the description of the rate at which a chemical reaction takes place, specifically the transformation of reactants into products. It f
The motivation was to better capture system dynamics than is possible based on the standard indices COP and specific heating/cooling power. The “true temperature boost” is based on a time averaging and as such is evaluated in terms of its mean and standard deviation. As an example, a two...
The fundamental discovery in the 1930s1that a protein’s intracellular concentration is based on a continuous interplay between synthesis and degradation resulted in an ever-growing interest in methods to measure the concentration of a given protein as a function of time. Progressively, an array of ...
In all of these examples, the reaction outcome is altered by changing the initial excitation mechanism. The ensuing dynamics are allowed to evolve naturally from this point but with only one possible reaction outcome. Here, within an excitation energy window, we keep both the initial conditions ...
usually share a common beta-barrel fold, originally found in GFP15. Despite their molecular weight in the range of 30 kDa, which is often larger than their fusion partner, they are often considered bystanders. Multiple examples, however, indicate influences on experimental outcomes16,17,18,19,...
E22G carriers exhibit senile plaques and 1School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8503, Japan. 2RIKEN Center for Biosystems Dynamics Research, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, ...
The unit of time is normalized with the inverse of the mRNA degradation rate, and therefore time is non-dimensional: it is measured in units of the mRNA half-life (see Figure 2A for mRNA dynamics). All mRNA and protein degradation rates are constants in model 1 with a fixed value of 1...
RNA levels detected at steady state are the consequence of multiple dynamic processes within the cell. In addition to synthesis and decay, transcripts undergo processing. Metabolic tagging with a nucleotide analog is one way of determining the relative c
Based on the fact that in coal flotation the flotation dynamics reflecting the speed of the flotation process, the analysis of the dynamic model is a crucial issue concerning the industrial practice that will occur. The research on flotation dynamics mainly focuses on the changing rule of flotation...
In this review, we introduce and compare computational methods recently developed and applied to two systems, trypsin–benzamidine and kinase–inhibitor complexes. Methods involving enhanced sampling in molecular dynamics simulations or machine learning can be used not only to predict kinetic rates, but ...