Belonging to the Kinesin-like protein family, KIF19 is a 998 amino acid protein that contains one kinesin- motor domain, a domain that creates force ... Kozielski,Thormählen,Schönbrunn,... 被引量: 0发表: 0年 Exclusive expression of C. elegans osm-3 kinesin gene in chemosensory neuron...
The KIF3 motor transports N- cadherin and organizes the developing neuroepithelium. Nat Cell Biol 2005; 7:474-482. 7 Hunter AW, Caplow M, Coy DL, et al. The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends. Mol Cell ...
A database search for potential homologs of the Kin I family in the entire genome sequence (The Sanger Centre, Hixton, UK) revealed that fission yeast possesses two members, which are named Klp5 and Klp6 (kinesin-like protein). Both proteins show 38% identity to human Kin I/MCAK or Xen...
Kinesin-like Protein KIF11doi:10.1007/978-3-540-47648-1_3222KSP Mitotic Spindle Motor ProteinSpringer Berlin Heidelberg
Second, the translation initiation codon of the pp250 cDNA predicts a highly conserved NH2 terminus among the KIF1 subfamily of kinesin superfamily of protein including the Drosophila kinesin-73. Third, the molecular weight of in vitro translated products of defined segments of full-length cDNA ...
The central motor kinesin superfamily has not been identified in humans. Murine KIF2 is a two-headed 81 kDA protein which moves toward the microtubule plus end at a speed of 0.4 μm/s. This kinesin-related protein is non-neuron-specific, but is expressed in the juvenile nerve system where...
While the majority of kinesin motors transport cargo selectively into axons, we identified five members of the kinesin-3 (KIF1) and kinesin-4 (KIF21) subfamily that can also target dendrites. We found that microtubule-binding protein doublecortin-like kinase 1 (DCLK1) labels a subset of ...
The mRNA encoding nucleolin (Ncl) was detected in neurites and markedly mis-localized after CTG480, Kif1bα tail, and Kif1c tail over-expression (Fig.3d). Nucleolin, an RNA binding protein, inhibits axonal growth of sensory neurons through localization of importin β1 RNA and is present in...
We sought to replicate the association between the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism (rs20455), and clinical coronary artery disease (CAD).BackgroundRecent prospective studies suggest that carriers of the 719Arg allele in are at increased risk of clinical CAD compared with non...
Kinesin family member C1 (KIFC1/HSET), a centrosome clustering protein that prevents cancer cells from undergoing centrosome-amplification-induced apoptosis, has been reported to be upregulated in TNBCs and African-American (AA) TNBCs. Herein, we analyzed KIFC1 RNA levels and their associations ...