Anakinra (Kineret), a recombinant form of human interleukin-1 (IL-1) receptor antagonist, is approved for the treatment of rheumatoid arthritis (RA) in combination with methotrexate. Kineret is self-administered by daily subcutaneous injections in patients with active RA. The mechanism of action ...
Mechanism Of Action KINERET blocks the biologic activity of IL-1 alpha and beta by competitively inhibiting IL-1 binding to the interleukin-1 type I receptor (IL-1RI), which is expressed in a wide variety of tissues and organs. IL-1 production is induced in response to inflammatory stimuli...
How does Kineret work (mechanism of action)? Kineret works by blocking the effects of a substance called interleukin-1 (IL-1). This substance is normally made by the body and is part of your body’s response toinflammation. Blocking the effects of this substance can help treat the symptoms...
Mechanism of Action Interleukin-1 receptor antagonist (recombinant E. coli-derived product) Blocks activity of IL-1 alpha and beta by competitively inhibiting IL-1 binding to the IL-1 type I receptor IL-1 production is induced in response to inflammatory stimuli and mediates various physiologic re...
12.1 Mechanism of Action KINERET blocks the biologic activity of IL-1 alpha and beta by competitively inhibiting IL-1 binding to the interleukin-1 type I receptor (IL-1RI), which is expressed in a wide variety of tissues and organs. IL-1 production is induced in response to inflammatory st...
How does Kineret work (mechanism of action)? Kineret works by blocking the effects of a substance called interleukin-1 (IL-1). This substance is normally made by the body and is part of your body’s response toinflammation. Blocking the effects of this substance can help treat the symptoms...
How does Kineret work (mechanism of action)? Kineret works by blocking the effects of a substance called interleukin-1 (IL-1). This substance is normally made by the body and is part of your body’s response to inflammation. Blocking the effects of this substance can help treat the symptom...
How does Kineret work (mechanism of action)? Kineret works by blocking the effects of a substance called interleukin-1 (IL-1). This substance is normally made by the body and is part of your body’s response to inflammation. Blocking the effects of this substance can help treat the symptom...