Visually, Code Black is on par with the original Cells at Work. Which is to say, it’s o.k. I wouldn’t call this a stunning anime and I doubt anyone will immediately point to Cells at Work when describing how beautifully animated shows can be, but it’s never turned me off either...
Here we explore in detail the complexity of NK cell biology in humans and highlight the role of these cells in cancer immunity. We also analyse the harnessing of NK cell immunity through immune checkpoint inhibitors, NK cell engagers, and infusions of preactivated or genetically modified, ...
Originally defined as cells that co-express αβ T cell antigen receptors (TCRs) and markers characteristic of natural killer (NK) cells such as NK1.1 (CD161), they have more recently been subdivided into at least three subsets [4]. Among these, the most abundant and well-studied are ...
Mature natural killer (NK) cells use Ca2+-dependent granule exocytosis and release of cytotoxic proteins, Fas ligand (FasL), and membrane-bound or secreted cytokines (tumor necrosis factor [TNF]-α) to induce target cell death. Fas belongs to the TNF receptor family of molecules, containing a...
Decidual natural killer cell tuning by autologous dendritic cells Problem:Dendritic cells (DC)/natural killer (NK) cells interactions in the deciduas of early human pregnancies were analyzed in vitro. Method of study:Phen... G Laskarin,A Redzovi,Z Rubesa,... - 《American Journal of ...
At the loci of inflammation or tumorigenesis, the NK cell interacts with possible target cells through interaction of integrins, in particular, LFA-1. During interaction with a potential target cell, the NK cell receptor repertoire determines the outcome of the ...
where they mature. This model is based on the fact that NK cell precursors have been found in several peripheral tissues such as the guts, uterus and liver [12]. Nevertheless, it is established that the compartment in which NK cells migrate drives their maturation to grant them tissue-specifi...
The meaning of LYMPHOKINE-ACTIVATED KILLER CELL is a lymphocyte (as a natural killer cell) that has been turned into a tumor-killing cell by being cultured with interleukin-2 —called also LAK.
Natural killer (NK) cell stimulatory factor or IL-12 has differential effects on the proliferation of TCR-alpha beta+, TCR-gamma delta+ T lympho- cytes, and NK cells. J Immunol 1992; 149:3495-502... B Perussia,SH Chan,A D'Andrea,... - 《Journal of Immunology》 被引量: 739发表...
They target a large fraction of T cell pools to set in motion a "cytokine storm" with severe and sometimes life-threatening consequences... CR Shaler,C Joshua,PT Rudak,... - 《Plos Biology》 被引量: 15发表: 2017年 A divergent response of innate regulatory T-cells to sepsis in humans:...