Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses. Blood 2003;101:3628 - 3634.Li H. Y., Appelbaum F. R., Willman C. L., Zager R. A., Banker D. E. (2003). Cholesterol-modulating agents kill acute...
High activity of the mechanistic target of rapamycin (mTOR) is associated with poor prognosis in pre-B-cell acute lymphoblastic leukemia (B-ALL), suggesting that inhibiting mTOR might be clinically useful. However, emerging data indicate that mTOR inhibitors are most effective when combined with oth...
cells is dependent on cell-to-cell contact To clarify whether the killing of influenza virus-infected A549 cells by Vc9Vd2-T cells requires cell-to-cell contact, we applied a transwell culture system to separate virus-infected A549 cells from Vc9Vd2-T cells at an E/T ratio of 20 : 1....
we expect that the pangenome matrix can be used for molecular characterization of different subtypes ofE. coli. The frequency or distribution of a gene family across all the genomes is expected to follow U-shape distribution
Cells were stained with a PE-conjugated anti-RAE-1γ antibody (eBioscience, CA, USA) or PE-conjugated rat IgG2b kappa antibody (eBioscience, USA) and then subjected to flow cytometric detection. Preparation of tumor cell lysates As established leukemia cell lines, BP210-mock, BP210-RAE-1...
A letter to the editor is presented regarding the death of tumor cells by acute myeloid leukemia-targeted toxins via cell type-specific mechanisms and manipulation of the extent and mechanism of the tumor cell death.HoritaDepartment of PharmacologyH....
HagenbeekNewENewJNewFeldmanNewMNewAndreeffNewKargerActa HaematologicaArlin ZA, Hagenbeek A, Feldman E etal. (1989) Implications of leukemia cell kill for the treatment of acute myelogenous leukemia (AML): can the cure rate be increased? Acta Haematol (in press)...
Acute myeloid leukemia (AML) is an aggressive blood cancer. With low survival rates, new drug targets are needed to improve treatment regimens and patient outcomes. Pseudolaric acid B (PAB) is a plant-derived bioactive compound predicted to interact with cluster of differentiation 1...
Roach, D.R.; Donovan, D.M. Antimicrobial Bacteriophage-Derived Proteins and Therapeutic Applications. Bacteriophage 2015, 5, e1062590. [Google Scholar] [CrossRef] [Green Version] Loessner, M.; Kramer, K.; Ebel, F.; Scherer, S. C-Terminal Domains of Listeria Monocytogenes Bacteriophage Murei...
Secondary myeloid/NK cell acute leukemiaZhijian XiaoXiaoming SunLiping JingHuishu ChengYushu HaoTaylor & FrancisLeukemia & LymphomaXiao, Z, Sun, X, Jing, L, Cheng, H, Hao, Y (2004) The successive development of acute myeloblastic leukemia, secondary non-Hodgkin’s lymphoma and secondary ...