We show how to use these weights in kidney exchange market clearing algorithms. We then evaluate the impact of the weights in simulations and find that the precise numerical values of the weights we computed matter little, other than the ordering of profiles that they imply. However, compared ...
In humans the kidneys are about 10 centimetres long and are located beneath the diaphragm and behind the peritoneum. Each kidney contains 1,000,000–1,250,000 nephrons that filter the entire five-quart water content of the blood every 45 minutes—an equivalent of 160 quarts a day. Of this...
Probes with missing values in more than 20% of samples, non-unique 30 bp 3’-subsequence, low mapping quality, inconsistent extension base fluorophore, extension base SNPs causing a color channel switch, non-CpG sites, and SNPs on chromosomes X, Y, and M, as well as global monomorphic ...
Kidney Created in Lab Raises Hopes for Humans ; Transplanted into Rat, Organ Was Able to Produce UrineJohnson, Carolyn Y
Nicotinamide adenine dinucleotide (NAD+) extends longevity in experimental organisms, raising interest in its impact on human health. De novo NAD+ biosynthesis from tryptophan is evolutionarily conserved yet considered supplanted among higher species by
Synthesis of Tyr in the human body occurs by hydroxylation of the indispensable amino acid Phe. Until now, it was believed that in humans, this process was restricted to the liver, but we provide compelling evidence of production of Tyr from Phe in the kidney. To determine whether the human...
After excluding patients on dialysis at time of procedure due to failed transplant and who did not have post-exposure creatinine values within 3 days, we reviewed 77 procedures on 57 patients. We studied one case per patient (the most recent procedure). Among the 57 patients, 42 were male,...
BACKGROUND: Effects of flaxseed on serum lipids have been studied in humans, but the results are variable. Flaxseed is ineffective in lowering blood pressure in rats. Its effect on blood pressure in humans is not known. It is also not known if long-term use of flaxseed in humans has delet...
the goal should be to reduce bias in anchoring the definition of AKD and its recovery. Towards that end, the use of known creatinine values is superior to imputation41. For patients in whom one or more pre-morbid serum creatinine values are available but show significant fluctuation, the choi...
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary nephropathy in humans1. Most patients with ADPKD are born healthy, but progressive cystic transformation of both kidneys induces a continuous decline in renal function leading to kidney failure1. Mutations in two genes,...