However, some small tumors are aggressive, grow quickly and spread to other organs. Surgery will not ‘get it all’, as the spread can occur well before the discovery of the mass. In addition, a “small” kidney tumor can be up to 7cm (2 3/4″) in size and have had years of sil...
055 122.76 108.2 0.0016* Conclusions: Evaluation of non-tumor renal tissue at the time of radical nephrectomy offers valuable predictive information regarding post-operative renal function. Significant pathological findings were common in our patient cohort. Our data suggest an ANNUAL MEETING ABSTRACTS ...
Clinical and follow-up information were obtained from the medical records. Gross findings were obtained from the surgical pathology reports. The percentage of the epithelial lining cells: biliary, intestinal and foveolar, was estimated for each tumor. Multiple H&E stained sections were available for ...
Clinical indicia which may be combined with the proUGN biomarker assay result(s) of the present invention includes demographic information (e.g., weight, sex, age, race), medical history (e.g., family history, type of surgery, pre-existing disease such as aneurism, congestive heart failure,...
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The identification of immune “checkpoints” (PD-1/CTLA-4) whose blockade stimulates anti-tumor immunity has changed outcomes for many ptients. However, immune checkpoint inhibitors (ICIs) produce novel response patterns across cancer types and can cause inflammatory side-effects known as immune-...
and by DK53465 and DK61594, and VA Merit Review, to BAM. Charles P Vega, University of California, Irvine, CA, is the author of and is solely responsible for the content of the learning objectives, questions and answers of the Medscape-accredited continuing medical education activity associa...
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The total RNA was isolated from the frozen renal cortices of mice or HK2 cells using TRIzol reagent (Invitrogen, USA). cDNA was then synthesized using PrimeScript RT Reagent Kit (Takara, Japan). The target genes (tumor necrosis factor α, TNFα; monocyte chemotactic protein-1, MCP-1; IL-...