【007】Kidney Functions in human body - video for kids 05:12 8 【008】parts of body name - Kindergarten,Preschool & Junior Kids 02:03 9 【009】Respiratory System - How we breathe - Video for kids 03:04 10 【010】Skeletal System - Human Skeleton 04:06 11 【011】The Nervo...
Given the similarities in size and filtration between the human sexes, to what extent might sex differences in renal transporter expressions alter segmental solute and transport patterns? To answer that question, we conduct model simulations under control conditions and compare solute and water transport...
Initial research studies have focused on the impact of PM2.5on respiratory and cardiovascular diseases; nevertheless, an increasing number of data suggested that PM2.5may affect every organ system in the human body, and the kidney is of no exception. The kidney is vulnerable to particulate matter...
As necessity is the mother of innovation, advances in protocols using human pluripotent stem cells (hPSCs) have generated complex three-dimensional, multicellular, and organ-specific tissue, termed organoids. Liver, lung, heart, intestines, and kidney organoids permit experimentation in human tissues ...
In 202,702 participants aged ≥ 60 years from the UK Biobank, Cox proportional-hazards models were used to examine the associations between eGFR and urine albumin creatinine ratio (ACR) with risk of incident dementia. GFR was estimated based on serum creatinine, cystatin C, or both. The ...
Kidney diseases remain one of the leading causes of human death and have placed a heavy burden on the medical system. Regulated cell death contributes to the pathology of a plethora of renal diseases. Recently, with in-depth studies into kidney diseases
in mouse and human, particularly the heterogeneity and differentiation processes of myofibroblasts, the role of injured epithelial cells and immune cells, and their crosstalk mechanisms. In this review we summarize the key mechanisms that drive kidney fibrosis, including recent advances in understanding ...
Diabetic nephropathy has been traditionally diagnosed based on persistently high albuminuria and a subsequent decline in glomerular filtration rate (GFR), which is widely recognized as the classical phenotype of diabetic kidney disease (DKD). Several studies have emphasized that trajectories of kidney func...
The kidneys are among the organs in the body that age most rapidly. In recent years, the role of renal parenchymal cell senescence in kidney disease has gradually gained attention. Various pathogenic factors stimulate the senescence of renal parenchymal cells, including tubular, mesangial, endothelial...
We decellularized rat, porcine, and human kidneys by detergent perfusion, yielding acellular scaffolds with vascular, cortical and medullary architecture, collecting system and ureters. To regenerate functional tissue, we seeded rat kidney scaffolds with epithelial and endothelial cells, then perfused these...