E-Figure 11-1.Effect of Ischemia on Cell Structure and Function. A polarized renal proximal tubule cell with a well-developed actin corticalcytoskeletonis shown on theleft. Also shown is attachment to theextracellular matrix(ECM) viaintegrins. Following ischemic injury there is extensive disruption,...
A detailed mechanism of hepatocyte growth factor (HGF)–induced MDCK cell tubulogenesis model has been described (188). There appear to be two steps involved in this process of invasion: epithelial–mesenchymal transition and the reestablishment of epithelial intercellular junctions. However, it has...
detailed image of the kidneys and other organs, a kidney biopsy where a small piece of 1093 Words 5 Pages Good Essays Read More Health and Social Care Unit 3 Ao1 D Promoting Good Health Essay The job of a kidney is to filter the blood and get rid of waste products; it also balances...
All data generated or analyzed during this study are included in this published article and its supplementary information files. Additional experimental details and more detailed data used or analyzed during the current study are available from the corresponding author upon reasonable request.Abbreviations...
Detailed results are summarized in Table 1. Patient demographics (n=81) Male Female Age (range) Deceased donor Living unrelated donor Living related donor Biopsy/clinical characteristics (n=141) Time after transplant (range) Protocol biopsies Cause biopsies Proteinuria Banff diagnoses (n=141) Non-...
4). Detailed investigation of monocytes-derived EVs and their cargo remains the objective of further study. The process of autophagy was activated in iPSCs co-cultured with monocytes, similar to the application of rapamycin. Cell survival was also dramatically improved by monocytes and macrophages (...
and arginine (targetingADC) has been approved for the prevention of kidney injury. Other drugs are approved for the prevention or treatment of tumours, nutritional deficiencies, psychiatric disorders, menopause, and various other conditions. Detailed information on these drugs is summarized in TableS8....
conduct all experiments on the same animal, with continuous monitoring of its well-being [139]. Using human tissue and organs also raises similar ethical questions, emphasizing the importance of providing a completely detailed informed consent form to the patients, informing them about the process, ...
m Representative maximal intensity projection (MIP) images and detailed molecular images of NDUFS4 (red) and STOML2 (green) by STORM in cultured podocytes under the same conditions as shown in Fig. 5j. Scale bars: 10 μm (left panel) and 500 nm (right panel). n Percent co...
Further, detailed calcium balance studies are needed in children and young adults with CKD, where the mineralizing bone requires a higher calcium intake. Calcium may be a protective factor against bone fragility and demineralization as suggested in some clinical studies [63]. In this population, per...