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The average length of the kidney is 20 mm at 20 weeks' gestation and increases by approximately 1.1 mm per week thereafter. • Abnormalities in size may be a normal variant; may represent compensatory hypertrophy; or may be a manifestation of a renal anomaly, infection, tumor, growth...
stone former pre-operative urine compared to healthy control urine, stone former OR urine, and stones (Benjamini–Hochberg corrected Wilcoxon testP < 0.05, ANCOM W value > 0.7 threshold, ALDEx2 GLM effect size >|0.5|). Data represent the median and IQR; HC (n = 25), SF...
Full size image Covariate analysis of hypoxia according to sex Box plots showing the effect of gender on condition (Hypoxic vs. Normoxic), using two-way ANOVA. Full size image Biomarker discovery Biomarkers identified using the biomarker discovery feature of MetaboAnalyst 5.0. ...
The detailed screening of studies for the meta-analysis and systematic review are presented in the flow chart (Fig. 1). Fig. 1 Flowchart of study selection Full size image Study characteristics The main characteristics of the selected studies are summarized in Table 1. The publication year of ...
well as inhibiting calcium oxalate stone formation through the inhibition of ferroptosis [170]. This study also demonstrated the role of ferroptosis in obstructive nephropathy. With an increase in calcium oxalate concentration, the expression of p53, ACSL4 and TRC in renal tubular epithelial cells inc...
43. Lockstone, H. E. Exon array data analysis using Affymetrix power tools and R statistical software. Brief Bioinformatics 12, 634–644 (2011). 44. Smyth, G. K. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Mol...
Subjects were followed with telephone calls, imaging, and chart review for adverse events. Results: The investigative treatment was used in 18 subjects and 19 kidneys. A total of 62 stone targets were treated ranging in size from a collection of "dust" to 15 mm. Subjects received an average...
Full size image The L381P renin variant induces ER stress and the Unfolded Protein Response Previous functional study on L16del renin mutant, a dominant renin mutant isoform responsible for ADTKD, showed that its expression induces the UPR, a cellular response to perturbed ER homeostasis4. In pa...
Stone, A. B. A simplified method for preparing sucrose gradients. Biochem. J. 137, 117–118 (1974). Article CAS PubMed PubMed Central Google Scholar Harbers, M. et al. Comparison of RNA- or LNA-hybrid oligonucleotides in template-switching reactions for high-speed sequencing library prepar...