Third, the kidney excretes metabolic by-products and exogenous substances, including certain drugs. Finally, the kidney is an important endocrine organ, producing key hormones involved in the regulation of blood pressure and erythropoiesis, as well as calcium, phosphate, and bone metabolism. The ...
第三节肾脏泌尿功能的调节 Regulationofurineformationofthekidney 中山大学基础医学院生理学教研室 王庭槐 尿生成的调节regulationofurineformation 肾血流量的调节 神经—体液调节 regulationofrenalbloodflownervousandhumonalcontrol (对滤过的调节) (对重吸收和分泌) 自身神经体液 调节调节调节ADH醛固酮甲状旁腺素 Aldostero...
patients can have complications related to fluid, electrolytes (minerals required for many bodily processes), and waste build-up in the body. Chronic kidney disease
Rudolph Heidenhain (1834–1897), however, strongly influenced by correlations between blood flow and urine formation and by staining of tubular cells by various dyes, believed that the production of urine was entirely compatible with a set of secretory processes similar to those of most exocrine ...
Similar subcapsular transplantation of kidney organoids has been repeated, demonstrating vasculature within the glomeruli of organoids persistently derives from the host and the formation of an early glomerular basement membrane consisting of fenestrated endothelial cells and podocyte foot processes [71]. A...
forbiopsy. In many cases, the extent ofpyelonephritis(inflammation in the kidney and the lining of therenal pelvis) that is a direct result of recurrent UTI is not known with certainty. However, it is known that, in the presence ofurinary tract obstruction, which disrupts the flow of urine...
The efficiency of renal O2 utilization was approximated by the ratio of total tubular transport of Na (TNa) − accounting for the vast majority of energy consuming processes in the kidney20-, and VO2, with TNa being equal to filtered Na minus excreted Na: $${\text{TNa}} = \left( {...
and other processes. In the kidney, the generation mechanism of adenosine triphosphate (ATP) is mainly determined by the cell type. For example, endothelial cells, podocytes, and mesangial cells use glucose to produce ATP. Renal tubular epithelial cells (TECs), critical to metabolite reabsorption,...
Optimising GMP manufacturing processes for cell therapies while transferring from the laboratory to an industrial scale is an evolving process. Moreover, to enable widespread use of these regulatory cell therapies in routine clinical practice, GMP cell manufacturing protocols need to be transferred to mu...
Mfn2 is involved in the regulation of cell proliferation, apoptosis and many other different biological processes23. Up regulation of Mfn2 protein expression reduces apoptosis in hepatic I/R injury24. In the current study, we found that Mfn2 overexpression significantly reduced Ca2+ overload in I...