Your kidneys job is to remove the extra wastes and fluids, including urea, from your body in the form of urine. When they do not do this, the fluid retention and waste build up products can leave you with dangerous changes to your body that can even beco
Fig. 1: Joint scRNA and scATAC profiling of bat kidney. A Representative phylogenetic tree showing the evolution of frugivory in bats (order: Chiroptera) (created with BioRender.com). The beetle denotes lineage with insectivorous diet, and banana denotes lineage with frugivorous diet. Numbers are...
Throughout this process, renin progenitors regulate branching and elongation of the kidney vasculature, where they are distributed broadly along large intrarenal arteries, in newly appearing arteriolar branches and inside the glomeruli in what later will become the glomerular mesangium [56]. Thus, ...
Denis Noble, who recently hailed Bernard as the first pioneer systems biologist in his monograph, cited Bernard: ‘The control of the milieu intérieur meant not that the individual molecules did anything different from what they would do in non-living systems, but rather that the ensemble ...
Table S3 summarizes the total cases investigated in rounds 1 and 2 of examinations and numbers of CKD cases defined by various criteria of KDIGO. Proportions of CKD according to criteria of persistent eGFR < 60 mL/min/1.73 m2 were 39.2%, albuminuria 49.0%, hematuria 17.1%, and abnormal...
(2014) to calculate the means and SD, respectively using Hozo et al. method [18]. We calculated the effect size from the reported events numbers. Risk of bias assessment Included studies' risk of bias was assessed using the Cochrane Collaboration’s risk of bias scale that addresses six ...
There have only been a few studies of pregnancy risk postdonation [100,101,102,124,125]. Studies have been limited by low numbers of events, and the design has generally been restricted to a before-and-after study design which may result in an over estimation of risk. ...
The mean dose of vasopressin was 0.06 U/min, and the mean dose of norepinephrine or epinephrine was 0.55 µg/kg/min, when the potentially drug-related serious adverse events occurred. In view of the uncertainty about what is the ideal blood pressure to target in septic shock,18 clinicians...
Frac- ture numbers were too small to have power for statistical analysis across these three tertiles. There were no changes in renal function as assessed by changes in serum creati- nine or serum calcium concentrations as a function of eGFR during the registration trial with the approved 20 mg...
Figure 2. Risk of chronic kidney disease (CKD) progression, frequency of visits, and referral to nephrology according to glomerular filtration rate (GFR) and albuminuria. The numbers in the boxes are a guide to the frequency of screening or monitoring (number of times per year). Green reflects...