resistant to three or more antibiotic classes, were calculated using a multivariable logistic regression model across eGFR strata. Of 94,445 total microbial culture records, 7,288 first positive cultures matched to infection diagnosis were selected. Among them, 5,028 (68.9%) were potential MDROs. ...
In addition to intensive care support, antibiotic treatment of PVL strains should include antibiotics which reduce toxin production, such as clindamycin, linezolid or rifampicin, as well as vancomycin if the strain is resistant to methicillin. Beta-lactam antibiotics should be avoided, as there is so...
Therefore, the same bundle of care needs to be implemented to limit the risk of potentially severe complications. This includes infection control procedures and checklists, learning and teaching safer vascular access by the use of ultrasound-guided insertion (real time), removing unnecessary catheters...
When to see a doctor for kidney infection If your only symptom is lower back pain, in many cases it will go away on its own. However, if the pain continues longer than four weeks or gets worse and is accompanied by fever, chills, or other symptoms of kidney infection, you should see ...
to antivenom and antibiotics, including highly active antiretroviral therapy; and the inability to provide timely and monitored management of hyperkalemia, acidosis, and fluid overload with diuretics increase AKI incidence, likely escalate the requirements for dialysis treatment, and lead to higher ...
Three months postoperatively, he was diagnosed to have tuberculous infection of his graft kidney manifested as fever and renal impairment. The diagnosis was confirmed by renal biopsy, which showed granuloma formation and positive stain for acid-fast bacilli (AFB). His systemic symptoms responded well...
For drugs freely filtered at the glomerulus, such as aminoglycoside antibiotics, renal elimination can be quite rapid. For many other drugs, binding to serum proteins restricts filtration and thus only the unbound fraction can be filtered and renal excretion is negligible. The limits to glomerular ...
The glycopeptide antibiotic vancomycin is a mainstay in the treatment of Gram-positive infection. While its association with acute kidney injury (AKI) has waxed and waned, recent data suggest nephrotoxicity, even as mono-therapy. Our study aimed to evalu
To evaluate the stability of the murine renal microbiota, we quantified alpha diversity of the kidney microbiome longitudinally for animals not exposed to antibiotics, similar to previous analyses in low microbiome echosystems36. While antibiotic exposure did not significantly change the number of microbi...
[41,71]. There is no strong evidence for any specific intervention affecting the course of AKI arising in the context of respiratory disease, although the early recognition of systemic or pulmonary infection followed by timely treatment with antibiotics is key [72], as is attention to adequate ...