has two important limitations. First, some CpG sites that are not strongly associated with kidney function by themselves could complement other sites to explain residual kidney function differences. These “auxiliary” sites cannot be identified by the single-site approach. Second, some significant CpG...
and used to diagnose and stage chronic kidney disease. To extend the knowledge on regulatory mechanisms related to kidney function and disease, we conducted a blood-based epigenome-wide association study for estimated glomerular filtration rate (n = ...
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In addition, proliferative PT may transmit signals of cell proliferation or anti-apoptosis to preserve kidney structure or function. However, proliferative PT did not interact with other PT populations in our DKD model, probably due to the limited numbers of proliferative PT in db/db mice. ...
Organoids are collections of cells in vitro that resemble a bodily organ in structure and function. These next-generation cell-culture systems remain highly accessible to experimental manipulation and analysis but are also sufficiently complex to model tissue-scale development, injury, and disease (Free...
The visual outputs are accompanied with quantitative measures that further provide estimation of the residual liver function and based on them the surgeons could make a better decision. The developed system was tested and verified with twenty abdominal CT patient sets consisting of different numbers of...
Furthermore, statistically significant higher values of uric acid, which is another biomarker primarily associated with kidney function, were found in DDHP with present CKD. Elevated levels of uric acid can lead to multiple organ dysfunctions through mechanisms of endothelial dysfunction, vascular smooth...
Our study has a number of limitations. First, additional experiments on the role of core genes are required. Second, the function and method by which lncRNA affects miRNA regulation on ntRNA need to be further elucidated. 5. Conclusions This study focused on ntRNA, a novel potential useful ...
There are many over-the-counter and prescription medications that will affect the results of your blood and urine kidney function test. Depending on your diet, this could affect the results of the test as well. This way you can insure that your kidney function numbers are being read correctly...
The results of your creatinine test are used to calculate your GFR. The GFR tells us your level of kidney function. Most adults have a normal rating of higher than 60 milliliters per minute. A rating of 60 milliliters per minute or lower might mean you have a loss of kidney function....