In a study of adults with normal kidney function, those who had frequent depressive symptoms were more likely to later experience a rapid decline in kidney function. The study will appear in an upcoming issue ofCJASN. Depression is a common condition in middle-aged andolder adults, and it can...
Renal Function Measurement Renal function may be assessed by measurement of serum creatinine or calculation or determination of the estimatedglomerular filtration rate(eGFR).Hydronephrosis, renal insufficiency, andurinary retentionappear with greater prevalence in patients with symptoms or signs of BPO. In ...
The average values of uromodulin excretion (2nd tertile) would represent cases where uromodulin failed to upregulate (or where the upregulation mechanism has been exhausted due to prolonged damage triggers), leading to a progressive decline in kidney function, possibly culminating in graft loss. ...
which might be reversed. On the other hand, the symptoms of chronic kidney failure may not appear until there is only a bit of kidney function left and can be permanent.
It has been shown that kidney function declines faster in men than women, possibly due to the renoprotective role of estrogens and progesterone [31] and to unhealthier lifestyles in men or the damaging effects of testosterone [32]. Furthermore, when considering specific CKD phenotypes, it is ...
Overall, our results indicate that monoallelic variants of ALG5 lead to a disorder of the ADPKD-spectrum characterized by multiple small kidney cysts, progressive interstitial fibrosis, and kidney function decline.doi:10.1016/j.ajhg.2022.06.013American journal of human genetics...
Somewhat paradoxically, there seems to be a preponderance of men among patients starting renal replacement therapy (RRT); the protective effects of oestrogens in women and/or the damaging effects of testosterone, together with unhealthier lifestyles, might cause kidney function to decline faster in ...
et al. Metabolites associate with kidney function decline and incident chronic kidney disease in the general population. Nephrol. Dial. Transplant. 28, 2131–2138 (2013). Article PubMed CAS Google Scholar Clarke, G. et al. The microbiome-gut-brain axis during early life regulates the ...
Ojo AO, Hanson JA, Wolfe RA et al (2000) Long-term survival in renal transplant recipients with graft function. Kidney Int 57:307–313 Article CAS PubMed Google Scholar Naylor AR, Ah See AK, Engeset J (1989) The morbidity and mortality after aorto-femoral grafting for peripheral limb is...
Although not typically observed in the native kidney, as lack of clinical signs or symptoms preclude biopsy at this point, an even earlier stage of deposits (stage 0) has been described in the kidney allograft13 when very fine IgG deposits can be detected by the highly sensitive IF in the ...