SYDNEY, May 18 (Xinhua) -- A randomised controlled trial in IgA nephropathy has found that a cheap and widely used corticosteroid drug halves the risk of losing kidney function and kidney failure. The study, led by the George Institute for Global Health, was a double-blinded, randomised, con...
Associations between kidney function and dementia risk are inconclusive. Chronic kidney disease (CKD) severity is determined by levels of both estimated glomerular filtration rate (eGFR) and the urine albumin to creatinine ratio (ACR). However, whether there is a graded increase in dementia risk for...
The single-site approach described above, though commonly used in the literature, has two important limitations. First, some CpG sites that are not strongly associated with kidney function by themselves could complement other sites to explain residual kidney function differences. These “auxiliary” sit...
damage in kidney tissue, exacerbates acute kidney injury, and further promulgates chronic kidney injury in murine models17,18,19. Further research is needed to further define the mechanistic pathway(s) in which PM2.5adversely affect kidney function and contributes to the biology of CKD. The magnit...
"Diabetes is the leading cause of kidney failure worldwide but for almost two decades there have been no new treatments to protect kidney function," he said. "This definitive trial result is a major medical breakthrough as people with diabetes and kidney disease are at extremely high risk of...
Kidney transplantation increased HDL (p< 0.0001) and decreased triglyceride (p= 0.007) concentration, whereas there was no significant change in LDL and total cholesterol. These effects were dependent on maintenance of graft function, statin therapy (those who were on) if graft failure occurred ...
20. As its function of water reabsorption, concentration and dilution, the kidney shows its significant character as water-transportation. 由于肾脏具有对水的重吸收、浓缩及稀释等功能,所以水的转运就成为肾脏的突出表现,同时肾脏血流灌注量也非常之大。
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Healthy ageing and the kidney — lessons from centenarians Centenarians — who are a putative model of healthy longevity — often have a low risk of cardiovascular disease, despite an age-associated decline in kidney function. An understanding of the molecular and cellular underpinnings of health kid...