When analysed separately, the results were similar for intact and ruptured AAA risk. Among the 638959 participants who had repeated eGFR tests, 3447 (0.54%) experienced AAA events, of which 217 (0.04%) were fata
and used to diagnose and stage chronic kidney disease. To extend the knowledge on regulatory mechanisms related to kidney function and disease, we conducted a blood-based epigenome-wide association study for estimated glomerular filtration rate (n = ...
The single-site approach described above, though commonly used in the literature, has two important limitations. First, some CpG sites that are not strongly associated with kidney function by themselves could complement other sites to explain residual kidney function differences. These “auxiliary” sit...
SYDNEY, May 18 (Xinhua) -- A randomised controlled trial in IgA nephropathy has found that a cheap and widely used corticosteroid drug halves the risk of losing kidney function and kidney failure. The study, led by the George Institute for Global Health, was a double-blinded, randomised, con...
Associations between kidney function and dementia risk are inconclusive. Chronic kidney disease (CKD) severity is determined by levels of both estimated glomerular filtration rate (eGFR) and the urine albumin to creatinine ratio (ACR). However, whether there is a graded increase in dementia risk for...
When healthy, the body's two kidneys work together to filter about 110 to 140 liters of blood and produce about 1 to 2 liters of urine every day. Dehydration or diseases like diabetes and high blood pressure impair kidney function and can result in serious medical conditions, including prote...
20. As its function of water reabsorption, concentration and dilution, the kidney shows its significant character as water-transportation. 由于肾脏具有对水的重吸收、浓缩及稀释等功能,所以水的转运就成为肾脏的突出表现,同时肾脏血流灌注量也非常之大。
DNA methylation (DNAm) is associated with gene regulation and estimated glomerular filtration rate (eGFR), a measure of kidney function. Decreased eGFR is more common among US Hispanics and African Americans. The causes for this are poorly understood. We
(4) Patients who have had a second AKI hit rarely recover their kidney function completely (full blue line), and have an increased risk of progressive CKD and evolution to ESKD over time (full lilac line). GFR=glomer...
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