Ahmed H. Abdelhafiz, et al, "Is chronic kidney disease in older people a new geriatric giant?" Aging Health, November, 2011.Abdelhafiz AH, Ahmed S, Flint K, El Naha M. Is Chronic Kidney Disease in Older People a New Geriatric Giant? Aging Health. 2011;7(5):749-762...
The prevalence of chronic kidney disease (CKD) steeply rises with age but there is controversy regarding the diagnosis and clinical significance of CKD in older people. This article reviews recent advances in our understanding with respect to the diagnosis, aetiology and adverse outcomes associated wit...
kidney disease is the eighth leading cause of death and is expected to become the fifth leading cause of death globally by 2040. At present, the incidence rate of kidney disease in China is 10.8%, and the population of chronic kidney disease is more than 100 million. The elderly...
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Ensuring access to life-sustaining maintenance dialysis therapy for individuals with irreversible kidney failure was the principle rationale for establishing the US Medicare end-stage renal disease (ESRD) entitlement in 1972. This government program, similar to the universal health care provided in other...
(AKI) is highest in elderly patients, who make up an ever-growing segment of the population at large. AKI in these patients is associated with an increased risk of short- and long-term death and chronic kidney disease, including end-stage renal disease. Whether AKI in older individuals ...
(HealthDay)—Current chronic kidney disease (CKD) definitions that do not consider age-related estimated glomerular filtration rate (eGFR) decline may inflate the burden of CKD in the elderly, according to a study published online Aug. 30 in JAMA Interna
Theincidencerateofacutekidneyinjury(AKI)ishighestinelderlypatients,whomakeupan ever-growingsegmentofthepopulationatlarge.AKIinthesepatientsisassociatedwithanincreased riskofshort-andlong-termdeathandchronickidneydisease,includingend-stagerenaldisease. WhetherAKIinolderindividualscarriesalargerrelativeriskfortheseoutcom...
metalloproteinases) [15]. Renal senescence occurs when senescent cells accumulate in the kidneys and chronic low-grade inflammation is induced. Chronic inflammation impedes intrinsic tissue regeneration and exacerbates renal damage, thus increasing the vulnerability of older adults to kidney disease and redu...
to test methods for assessing cost-effectiveness.#A deferred entry, randomised controlled feasibility trial, incorporating economic and process evaluations, with people with end-stage kidney disease, aged 65years or older, receiving haemodialysis, in two renal haemodialysis units in Northern Ireland, UK...