Irisin protects the cardiovascular system against vascular diseases. However, its role in chronic kidney disease (CKD) -associated vascular calcification (VC) and the underlying mechanisms remain unclear. In the present study, we investigated the potential link among Irisin, pyroptosis, and VC under C...
More than 800 million people suffer from kidney disease, yet the mechanism of kidney dysfunction is poorly understood. In the present study, we define the genetic association with kidney function in 1.5 million individuals and identify 878 (126 new) loci. We map the genotype effect on the methy...
Chinese medicine Enema Diabetic kidney disease Introduction Chinese medicine enema is an external treatment method of transanorectal administration in traditional Chinese medicine (TCM).1 It has long been used in the treatment of nervous, digestive, respiratory, endocrine, urinary and other systemic dise...
The related animal experiment flow chart is shown in Fig. 4A. In Fig. 4B-D, the mice treated with adenine plus trehalose concomitantly showed similar weight loss and increased plasma BUN and creatinine levels. Furthermore, trehalose did not prevent adenine-induced kidney injury as trehalose-...
(minimize detection bias as we avoid any controls who may have had unrecognized kidney disease due to absence of kidney function testing). We additionally will attempt to include family history of CKD at the index date (either through chart review or from survey results) as a factor in the ...
Tick titres were negative (She tested for lymes disease and rocky mountain fever and the test for leptospirosis was negative as well). It took three days for tick titres to get back, in the mean time she was given antibiotics intravenously with her fluids. Her bun and creatinine getting wors...
BUN: Blood urea nitrogen CKD: Chronic kidney disease ICU: Intensive care units GCS: Glasgow Coma Scale IQR: Interquartile range LAR: Lactate dehydrogenase to albumin ratio LDH: Lactic dehydrogenase MAP: Mean arterial pressure MIMIC IV: The Medical Information Mart for Intensive Care IV...
Acute kidney injury (AKI)-A clinical syndrome that is characterized by the rapid loss of renal function and can progress into chronic kidney disease (CKD) or even end-stage renal disease (ESRD)-is a major global public health problem.Citation1 AKI accounts for 10–15% of all hospitalized pa...
The duration of attempted conception, cause of end-stage renal disease (ESRD), time since the transplantation, and whether the patient had graft rejection and hypertension were assessed through a retrospective chart review. The time of data collection for each factor, including the type of ...
Brominated flame retardants (BFRs) Chronic kidney disease (CKD) Renal function indicators WQS and QGS 1. Introduction Chronic kidney disease (CKD) is irreversibly progressive syndromes over time with the prevalence of more than one in seven US individuals (Ammirati, 2020), which is interconnected wi...