此外,如果钙和磷酸盐同时得到不错控制,补充维他命K只能改善心肾脏人体内。 参考文献:Nadine Kaesler, Leon J. Schurgers, Jürgen Floege, Vitamin K and cardiovascular complications in chronic kidney disease patients, Kidney International, Volume 100, Issue 5, 2021, Pages 1023-1036, ISSN 0085-2538,...
UbiA prenyltransferase domain containing 1 (UBIAD1) is a novel vitamin K2 biosynthetic enzyme screened and identified from the human genome database. UBIAD1 has recently been shown to catalyse the biosynthesis of Coenzyme Q10 (CoQ10) in zebrafish and human cells. To investigate the function of ...
Kidney diseases remain one of the leading causes of human death and have placed a heavy burden on the medical system. Regulated cell death contributes to the pathology of a plethora of renal diseases. Recently, with in-depth studies into kidney diseases and cell death, a new iron-dependent ce...
Understanding how the microbiota influences host vitamin regulation could help to determine the role of vitamins in stone disease. This is a preview of subscription content, access via your institution Access options Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value...
Patients with chronic kidney disease (CKD) have an excessively high risk of cardiovascular disease [1], and accelerated large artery calcification of the media-intima is an important contributor to this [2]. Furthermore, patients with CKD are also prone to vitamin K deficiency which may be impl...
This study explored the self-management strategies and treatment burden experienced by low-income US primary care patients with chronic kidney disease. Sem... LS Kahn,BM Vest,N Madurai,... - 《Chronic Illness》 被引量: 12发表: 2015年 Vitamin D resistance in chronic kidney disease (CKD) Back...
Kidney cancer is frequently metastatic on presentation at which point the disease is associated with a 95%mortality. Assessment of tumor grade on pathological examination is the most powerful means for prognostication as well as for stratification of patients into those who might respond to ...
21 Genetic proxies of β-blockers and systolic blood pressure were chosen as negative controls because they have no known effect on urinary calcium excretion or kidney stone risk and were used as negative controls in previous observational studies of kidney stone disease.22 To proxy β-blockers,...
Matrix Gla protein (MGP) is a potent inhibitor of vascular calcification (VC) and requires carboxylation by vitamin K to exert calcification inhibition. Chronic kidney disease (CKD) patients undergo early vascular aging often involving extensive VC. The present cross-sectional study investigated the as...
Furthermore, osocimab was associated with low rates of clinically relevant bleeding, the composite of major and clinically relevant nonmajor bleeding14. To address the unmet need for safer anticoagulants for patients with end-stage kidney disease, we conducted the CONVERT trial (ClinicalTrials.gov ...