kidney cancerpathologic stage T3arenal cell carcinomaPurpose: Preoperative assessment of T3a renal-cell-carcinoma (RCC) in absence of main renal vein involvement or lymph node enlargement is challenging but has potential implications for counseling and prognosis. Materials and Methods: A retrospective ...
A 64 year old male is found to have an isolated enhancing 3 cm solid kidney mass on CT imaging with no evidence of lymph node involvement or metastatic spread. You are referring to the urology registrar on the telephone, who wants to know what stage his cancer appears to be. A. T1a; ...
The sensitivity was determined for each stage of cancer (yellow—T1, orange—T2, and red—T3), excluding samples with unknown cancer stage. Training set: (A) kidney cancer versus healthy control for males, (B) kidney cancer versus healthy control for females, (C) prostate cancer versus ...
Tumor grade Stage 0 (oncocytoma), 6; grade 1, 5; grade 2, 32; grade 3, 25; grade 4, 18 Tumor stage Stage 0 (oncocytoma), 6; T1 (a+b), 40; T2, 13; T3, 21; T4, 6 Metastasis at surgery Positive, 6; negative, 80 Lymph node Positive, 3; negative, 83 Renal vein involvement...
Fox Chase Cancer Center, 333 Cottman Avenue, H3 116, Philadelphia, PA, 19111, USA Daniel J. Canter & Robert G. Uzzo Corresponding author Correspondence toDaniel J. Canter. Editor information Editors and Affiliations Surgical Oncologist/Minimally Invasive S, Osborn Street 263, Philadelphia, 19128,...
AGO2, a key element of the RNA-induced silencing complex, can inhibit mRNA translation by binding to the m7G cap [26]. The AGO2 rs4961280 AA/AC genotype is considered a biomarker of poor prognosis in RCC and the expression level of AGO2 can effectively reflect kidney cancer invasiveness ...
The TIME, comprising cancer cells, stromal tissue, immune cells, cytokines, and other factors, has a close connection to tumor initiation and progression21,22. In this study, we separated patients with KIRC into two patterns according to the mRNA expression of ADME genes from TCGA-KIRC and val...
Fig. 1. TARBP1 in kidney renal clear cell carcinoma: the expression of TARBP1 in unpaired (A) and paired (B) pan-cancer; the prognostic value of TARBP1 (C–D); diagnostic value of TARBP1 (E); the prognostic value in subgroups of cancer-specific survival (F–H) and overall survival...
BCL-2-associated athanogene 3 (BAG3) is an anti-apoptotic protein that plays an essential role in the onset and progression of multiple cancer types. However, the clinical significance of BAG3 in kidney renal clear cell carcinoma (KIRC) remains unclear.
reflecting the presence of acute phase and inflammatory gene products in addition to the profibrotic and cell death gene products represented in the chronic kidney disease (CKD) stage 5, renal fibrosis and renal insufficiency ontologies. The heavily enriched peripheral vascular disease and endothelial da...