Furthermore, hyperkalemia (5.2 mEq/L), hyperphosphatemia (6.2 mg/dL), high levels of BUN (100 mg/dL), and creatinine rise (6.8 mg/dL) were found. Urine analysis showed 2+ blood, 4-6 red blood cells, and cola-colored urine. Based on the findings, drug-induced AHA, followed by ...
and neutrophil gelatinase-associated lipocalin (NGAL) and takes the Fe3+form (Fig.1). However, under pathological conditions, iron is readily involved a single electron transfer reaction and is transformed into ferrous iron, which shows high reactivity and toxicity. Unstable iron (mainly in the fo...
2a–c). Of note, mice subjected to IRI/CL-NX and mice subjected to U-IRI had equivalent creatinine levels on days 14 and 30, with BUN values that approached equivalence, suggesting nearly complete recovery of filtration function by the previously injured IRI/CL-NX kidneys as compared to the...
Administration of high-dose, intraperitoneal folic acid (FA) causes AKI.27,28 In the current study, FA injection into CD1 mice led to an increase in blood urea nitrogen (BUN) from 21±1 to 118±9 mg/dl (P<0.01) after 24 h compared with no change in vehicle-injected animals (Figure ...
Tubulointerstitial injury index, RIF, serum Scr, BUN level, and expressions of PERK, CHOP, and caspase-3 were different between the model and treatment groups (P < 0.05; P < 0.01). The expressions of PERK, CHOP, and caspase-3 in nephridial tissue were reduced (P < 0.05), ...
On the other hand, cre- atinine and BUN were analyzed respectively based on the Jaffé's kinetic colorimetric method and kinetic test with urease and glu- tamate dehydrogenase. The level of serum creatinine was then used to estimate glomerular filtration rate (eGFR) according to the 2009 CKD-...
UniversityofCincinnati OverviewofAKI DefinitionofAKIPathophysiology Pre-renalRenal:glomerular,tubular,interstitialandvascular.Postrenal:obstruction.ClinicalfeaturesInvestigationsTreatmentPrevention AKIDefinition SuddenrapiddropinGFR,asmeasuredbyserumcreatininelevel,overhourstodays.DiagnosticCriteriaforAKI AKI:StageI:StageII...
Objective:To observe the effect of Fufang Tufuling granules on serum level of uric acid(UA),urea nitrogen (BUN),creatinine(Cr), and the level of interleuki... 王天,孙维峰 - 《中国实验方剂学杂志》 被引量: 60发表: 2012年 Hypouricemic and arthritis relapse-reducing effects of compound tu...
(BUN). As shown in Fig.4c, d, SCr and BUN were elevated in mice after UIRI, which were reduced after KP1 treatments. As the side effect of Klotho is hypophosphatemia and hypocalcemia34, blood phosphorus, and calcium level were examined. As shown in Supplementary Table2, KP1 did not ...
229 kidney cells. Heritability analysis reveals that methylation variation explains a larger fraction of heritability than gene expression. We present a multi-stage prioritization strategy and prioritize target genes for 87% of kidney function loci. We highlight key roles of proximal tubules and ...