Hormone receptor status, HER2 status, and the Ki67 index (percentage of Ki67-positive cancer nuclei) were determined immunohistochemically. Receiver operating characteristic curves were used to determine the Ki67 cut point to distinguish luminal B from luminal A tumors. The prognostic value of the ...
This approach is easier and potentially more reproducible than counting the percentage of Ki67 positive cells. The information could be useful from a prognostic standpoint and may well be predictive of potential response to radiation, hormonal and targeted therapies. Wednesday, December 9, 2015 5:00...
(3a) The difference in percentage of Ki67-positive cells between surgical sample and core biopsy versus the corresponding mean for each of the 50 pairs. Two hundred cells were counted. The dashed line represents the average difference 3.9% and the solid lines a 95% reference interval around ...
(3a) The difference in percentage of Ki67-positive cells between surgical sample and core biopsy versus the corresponding mean for each of the 50 pairs. Two hundred cells were counted. The dashed line represents the average difference 3.9% and the solid lines a 95% reference interval around ...
Methods Tumors from a cohort of 357 patients with invasive breast carcinomas were subtyped by gene expression profile. Hormone receptor status, HER2 status, and the Ki67 index (percentage of Ki67-positive cancer nuclei) were determined immunohistochemically. Receiver operating characteristic curves were...
山东大学硕士学位论文 (二)鼻息肉、鼻腔内韶性乳头状瘤及鼻腔鳞癌组织中PCNA平均指数分 别为:29.47±9.29;35。45±7.02;63.18±12.17统计分析表明差异有显著性意义 (p<0。001)。在鼻腔内翻性乳头状瘤中PCNA阳性细胞多表达于瘤细胞的基底 层及中层,多不超过乳头状瘤的内2f3层,而在鼻腔鳞癌表达的阳性细胞数逐 ...
Whenever possible, up to 10 high-power fields were analysed and at least 500 tumour cells were counted to calculate the mean percentage of Ki67-positive tumour cells per analysed sample. Nuclear grading score was determined by a board certified pathologist (IS) as previously described by Kadota ...
The anti - OV-6 monoclonal antibody showed positive immunostaining in many of the cells expressing c- met pp. The percentage of Ki67+ nuclei in high-grade HCCs paralleled c- met protooncogene overexpression. The c- met pp in OV-6+ cells suggests that the paracrine mechanism postulated in ...
Ki67 analysis in primary breast cancer is known to be a prognostic marker for the > 80% of patients whose breast cancers are ER-positive [3] (ER +). Such an example is its licencing as a companion diagnostic for abemaciclib in the US[4]. Yet, where an individual patient’s ...
Sets of pre-stained core-cut biopsy sections of 30 breast tumors were circulated to 14 laboratories for scanning and automated assessment of the average and maximum percentage of tumor cells positive for Ki67. Seven unique scanners and 10 software platforms were involved in this study. Pre-...