[4]“Bruno, S, and Z Darzynkiewicz. “Cell cycle dependent expression and stability of the nuclear protein detected by Ki-67 antibody in HL-60 cells.” Cell proliferation vol. 25,1 (1992): 31-40. doi:10.1111/j....
关键词:细胞周期;流式细胞术;Ki67;4′,6‐二脒基‐2‐苯基吲哚;碘化丙啶ApplicationofKi67andnuclearacidfluorescentdyeco‐staininginanalysisofcellcycleSUNShuhuiDepartmentofMedicalMicrobiologyandParasitology,KeyLaboratoryofMedicalMolecularVirologyofMinistriesofEducationandHealth,SchoolofBasicMedicalSciences,Fudan...
Ki67是细胞增殖相关的核抗原, Ki67表达高低与细胞周期中的有丝分裂相关, 与肿瘤发展密切相关。Ki67在肿瘤组织中呈周期性高表达, 在正常组织中低表达, 是乳腺癌分子分型及预后重要指标, 目前有研究表明其在乳腺癌治疗中可用于评估治疗疗效及预后, Ki67是现有新辅助...
Ki67 is an intrinsic marker of ongoing cell proliferation and is present during all active phases ofthe cell cycle (G1-M). This antibody is polyclonal and was raised in rabbit to the human peptidesequence – TPKEKAQALEDLAGFKELFQT – that was coupled to thyroglobulin byglutaraldehyde before be...
The main reason making the tumor grow faster is the increase of proliferation cell ratio, which is called growth fraction. In surgical pathology, the cells in proliferation cycle can be labeled by Ki67 immunostaining. Generally speaking, the higher the Ki67 labeling ratio, the faster the tumor ...
Ki67 expression in different cell cycle phases.Jing Ping YuanLin Wei WangAi Ping QuJia Mei ChenQing Ming XiangChuang ChenShengRong SunDaiWen PangJuan LiuYan Li
[J].CellCycle, cytologyinthetriageofASCUSandLSILpapanicolaoucytology 2004,3(5)611615. resultsfromtheEuropeanequivocalormildlyabnormalPapanico [17]McLaughlinDrubinME,ParkD,MungerK.Tumorsuppressor laoucytologystudy[J].CancerCytopathol,2011,119(3)158 p16INK4Aisnecessaryforsurvivalofcervicalcarcinomacell...
(14):3689-3695.3 Pruitt K,Der CJ.Ras and Rho regulation of the cell cycle and oncogenesis.Cancer Lett,2001,71(1):1210.4 Bartek J,Lukas C,Lukas J.Checking on DNA damage in S phase.Nat Rew Mol Cell Biol,2004,5:792-804.5 Nakayama KI,Nakayama K.Ubiquitin ligases:cell-cycle control and...
背景介绍Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms...
山西医科大学硕士学位论文子宫富于细胞性平滑肌瘤ER、PR、Ki67表达及DNA含量与细胞周期研究姓名:***请学位级别:硕士专业:病理学指导教师:**民20070508山西医科大学硕士学位论文子宫富于细胞性平滑肌瘤ER、PR、Ki67表达及DNA含量与细胞周期研究摘要目的:探讨ER、PR、Ki67在子宫富于细胞性平滑肌瘤(cellularleiomyoma.CL)qal...