CD56,CD44 荧光强度与对照组比较明显降低(P<0.05),但是对KG-1a 细胞表面标志物CD7,CD56,CD44 表达率无明显影响,与对照组比较无统计学意义(P>0.05).结论:川芎嗪逆转白血病耐药作用,除能够降低MDR,P-gp 高表达外,能够降低白血病干细胞特异性表面标志物CD34+CD123+,CD34+CD33+,CD33+CD123+,CD7,CD56,CD44表达...
Utilizing cytokines including interleukin-2 (IL-2) and interleukin-15 (IL-15) to activate PBMCs, we obtained substantial CD3+ CD56+ natural killer cell-like T lymphocytes that secreted cytokine interferon-纬 (IFN-纬) and expressed NKG2D and TRAIL on their surfaces (i.e., cytokine-induced ...
<0. 01).给药48 h后,对照组与高剂量实验组KG-1a细胞CD7表达率分别为(94. 53±3. 67)%,(79. 86±5. 02)%;CD56表达率分别为(92. 93±4. 11)%,(89. 41±3. 89)%,差异均有统计学意义(均P <0. 01).结论川芎嗪可显著抑制小儿急性髓性白血病KG-1a细胞增殖,并可有效抑制其表面抗原CD7及CD56...
Utilizing cytokines including interleukin-2 (IL-2) and interleukin-15 (IL-15) to activate PBMCs, we obtained substantial CD3+ CD56+ natural killer cell-like T lymphocytes that secreted cytokine interferon- (IFN-) and expressed NKG2D and TRAIL on their surfaces (i.e., cytokine-induced killer...
Results: The percentages of NK cells in the peripheral blood before and after isolation with anti-CD3-CD56+ antibody-labeled immunomagnetic beads were (15.2 卤 3.7)% and (84.9 卤 5.5)%, respectively. The results of CCK-8 assay showed that the inhibitory effects of aclacinomycin on the ...
Utilizing cytokines including interleukin-2 (IL-2) and interleukin-15 (IL-15) to activate PBMCs, we obtained substantial CD3+ CD56+ natural killer cell-like T lymphocytes that secreted cytokine interferon-γ (IFN-γ) and expressed NKG2D and TRAIL on their surfaces (i.e., cytokine-induced ...