As described above, GPER1 is 6-fold induced in response to T1 treatment, and the importance of GPER1 in the Ca2+ signaling of the cardiovascular system is the subject of a recent review [180]. Obviously, GPER1 is part of a complex calcium signaling machinery [181], and its upregulation...
What are the key functions of the circulatory system in homeostasis? Homeostasis: All the cells, tissues, and organs function together to maintain homeostasis in the body. A Cell maintains the content of water and substances in the cytoplasm by homeostasis. Water content is balanced in the ...
To advance our understanding of immunology outside the haematopoietic system, here we systematically investigate the regulation of immune genes in the three major types of structural cells: epithelium, endothelium and fibroblasts. We characterize these cell types across twelve organs in mice, using ...
This pathological injury, which increases with aging, sustains a chronic inflammatory state of the cardiovascular system [45]. It favors the Warburg effect which sustains proliferation of vascular smooth muscle cells (VSMC) [46]. Atherosclerosis appears as a common comorbidity factor in severe COVID...
The connection between these two vital organs is largely based on their shared reliance on a healthy vascular system, along with common risk factors. By focusing on lifestyle adjustments like exercise, balanced nutrition and managing chronic conditions, you can reduce your risk for cardiovascular ...
We performed RNA-sequencing and transcriptomic analysis on 3D microvessel cell cultures exposed to simulated deep space radiation (0.5 Gy of Galactic Cosmic Radiation) with and without the antagonists to three microRNAs: miR-16-5p, miR-125b-5p, and let-7a-5p (i.e., antagomirs). ...
AstraZeneca will showcase new clinical and real-world data across its leading inhaled, biologic and early science respiratory portfolio at the American Thoracic Society International Conference, in San Diego, CA from May 17 - ...
The physiological control of appetite is mediated by circulating orexigenic and anorexigenic hormones (e.g., leptin, insulin, and ghrelin) produced by peripheral organs, including gut, adipose tissue, and pancreas. Here, we summarize the impacts of specific changes in the microbial compositions on ...
5 However, the poor availability of donated organs and some complications have limited its application. So, finding an effective way to replenish the loss of cardiomyocytes during heart attack has been a hot topic of interest. Cardiomyocyte plasticity plays a critical role in cardiac adaptive ...
Cardiovascular Physiology Control of the Heart The mechanical activity of the heart is precisely regulated in accordance with the electrical activity of the heart to effect optimal cardiac output to the organs of the body.9,10The electrical activity of the heart, based on electrocardiography, in bot...